Proximal tubular FHL2, a novel downstream target of hypoxia inducible factor 1, is a protector against ischemic acute kidney injury.

Four-and-a-half LIM domains protein 2 (FHL2) is an adaptor protein that may interact with hypoxia inducible factor 1α (HIF-1α) or β-catenin, two pivotal protective signaling in acute kidney injury (AKI). However, little is known about the regulation and function of FHL2 during AKI. We found that FHL2 was induced in renal tubular cells in patients with acute tubular necrosis and mice model of ischemia-reperfusion injury (IRI).

A nonaqueous all organic semisolid flow battery.

We report the first proof of concept for a nonaqueous, all-organic semisolid flow battery (SSFB) using suspensions of 10-methylphenothiazine@Ketjen black and thioxanthone@Ketjen black dispersed in tetraethylammonium hexafluorophosphate/acetonitrile as the cathode and anode, respectively. A proof of principle cell with an open circuit voltage of 2.35 V demonstrated an average coulombic efficiency of 83% within the voltage range 3.

An all organic redox flow battery with high cell voltage.

An all organic redox flow battery with 4,4'-dimethylbenzophenone (44DMBP) anolyte and 2,5-di--butyl-1,4-dimethoxybenzene (DBB) catholyte shows a high open circuit voltage of 2.97 V, and average coulombic efficiency of 72% over 95 cycles at a current density of 1 mA cm.

A systematic study of the co-solvent effect for an all-organic redox flow battery.

Benzophenone and 1,4-di--butyl-2,5-dimethoxybenzene are used as the anode and cathode active species respectively in an all-organic redox-flow battery. A number of organics as the co-solvents are applied in the electrolyte to improve the electrochemical performance of it. For all kinds of the mixed solvents, a lower content of acetonitrile leads to a higher solubility to 1,4-di--butyl-2,5-dimethoxybenzene and a lower conductivity.