Development and Validation of a Risk Score for Mild Cognitive Impairment in Individuals with Type 2 Diabetes in China: A Practical Cognitive Prescreening Tool.

Aim: Numerous evidence suggests that diabetes increases the risk of cognitive impairment. This study aimed to develop and validate a multivariable risk score model to identify mild cognitive impairment (MCI) in patients with type 2 diabetes mellitus (T2DM).

Methods: This cross-sectional study included 1256 inpatients (age: 57.

Associations between complexity of glucose time series and cognitive function in adults with type 2 diabetes.

Aims: To characterize the comparative contributions of different glycaemic indicators to cognitive dysfunction, and further investigate the associations between the most significant indicator and cognitive function, along with related cerebral alterations.

Materials And Methods: We performed a cross-sectional study in 449 subjects with type 2 diabetes who completed continuous glucose monitoring and cognitive assessments. Of these, 139 underwent functional magnetic resonance imaging to evaluate cerebral structure and olfactory neural circuit alterations.

Triptolide Reduces MDA-MB-231 Cell Metastasis by Attenuating Epithelial-Mesenchymal Transition through the ROCK/PTEN/Akt Axis.

Triple-negative breast cancer (TNBC) is a highly heterogeneous and invasive subtype of breast cancer. The prognosis of TNBC is poor because of its high distant metastasis rate. Triptolide is a type of diterpene trioxide natural compound with potential anti-tumor activities.

Comparative study of K-wire combined with screw vs. K-wire in the treatment of AO type B3.1 phalangeal fractures.

Purpose: The purpose of this study was to introduce the surgical method of K-wire combined with screw in the treatment of Arbeitsgemeinschaftfür Osteosynthesefragen (AO) type B3.1 phalangeal fractures and to compare its clinical, radiological and functional outcomes with K-wire fixation.

Methods: This was a retrospective comparative study.

Impact of Echinococcus granulosus Antigens on Monocyte Development and Dendritic Cell Differentiation.

Background: Different subtypes of dendritic cells (DCs) can induce different types of immune responses. Our previous study found that Echinococcus granulosus (E. granulosus) antigens (Eg.

Results after open lunate excision alone or in combination with palmaris longus tendon ball arthroplasty for the treatment of Kienböck's disease.

Purpose: This study aims to compare results after open lunate excision alone and in combination with palmaris longus tendon ball arthroplasty for the treatment of late-staged Kienböck's disease (KD).

Methods: This is a retrospective study using the prospectively collected data, and patients who had a discharge diagnosis of KD (stage IIIB based on Lichtman staging criteria) and underwent surgical treatment by lunate excision alone or in combination with palmaris longus tendon ball arthroplasty between January 2011 and December 2020 were included in this study. Variables of interest involved demographics, disease condition, operative procedure, and the outcomes evaluated at the last follow-up.

The Presence and Severity of NAFLD are Associated With Cognitive Impairment and Hippocampal Damage.

Context: Although cognitive impairment in nonalcoholic fatty liver disease (NAFLD) has received attention in recent years, little is known about detailed cognitive functions in histologically diagnosed individuals.

Objective: This study aimed to investigate the association of liver pathological changes with cognitive features and further explore the underlying brain manifestations.

Methods And Patients: We performed a cross-sectional study in 320 subjects who underwent liver biopsy.

Zhuidu Formula suppresses the migratory and invasive properties of triple-negative breast cancer cells via dual signaling pathways of RhoA/ROCK and CDC42/MRCK.

Ethnopharmacological Relevance: Zhuidu Formula (ZDF) is composed of triptolide, cinobufagin and paclitaxel, which are the active ingredients of Tripterygium wilfordii Hook. F, dried toad skin and Taxus wallichiana var. chinensis (Pilg) Florin, respectively.

Time-Distributed Attention Network for EEG-Based Motor Imagery Decoding From the Same Limb.

A brain-computer interface (BCI) based on motor imagery (MI) from the same limb can provide an intuitive control pathway but has received limited attention. It is still a challenge to classify multiple MI tasks from the same limb. The goal of this study is to propose a novel decoding method to classify the MI tasks of four joints of the same upper limb and the resting state.

Cannulated compression screw with versus without two K-wire fixation for treatment of scaphoid waist fracture nonunion.

Purpose: This study aims to introduce the "tripod" technique using cannulated compression screw and two anti-rotational K-wires for treatment of unstable scaphoid waist fracture nonunion, and to compare it with the single cannulated screw fixation technique in term of scaphoid union and surgical outcomes.

Methods: It was a retrospective study. From January 2014 to March 2020, 103 consecutive patients with scaphoid waist fracture nonunion treated with the tripod fixation and bone grafting (n = 45) or with single cannulated compression screw and bone grafting (n = 58) were included.

Quercetin promotes cutaneous wound healing in mice through Wnt/β-catenin signaling pathway.

Ethnopharmacological Relevance: Oxytropis falcata Bunge is a legume distributed in Northwest China, which is mainly used to treat knife wounds and inflammation. Quercetin is a bioactive flavonoid in O. falcata and becomes a promising healing compound for its angiogenic and anti-inflammatory activities.

A Multi-response Aluminum Metal-organic Frameworks for Fluorescence Sensing of Fe, Sr, SiOand Toluene.

A new Aluminum metal-organic frameworks(Al-MOF) based on tricarboxylate ligands(L){L = 2,2',2'-([1,3,5]-triazine-2,4,6-triimino)tribenzoic acid)} has been designed and synthesized. It can be served as a platform of multi-responsive fluorescence sensor for Fe, Srand SiOin water, which is mainly due to the significant enhancement effect of these ions on the fluorescence intensity of Al-MOF. Especially, Feions are rarely able to induce MOFs fluorescence enhancement.

Determinants of anxiety and depression in patients with cubital tunnel syndrome.

Background: The aim of this cross-sectional study to assess the proportions of anxiety and depression in patients with CuTS, and to explore the associated demographic and clinical features.

Methods: From May 2011 to January 2017, 246 patients diagnosed with CuTS were recruited. The Hospital Anxiety and Depression Scale was used to assess the proportions of depression and anxiety.

A Transfer Learning Framework for RSVP-based Brain Computer Interface.

Rapid Serial Visual Presentation (RSVP)-based Brain-Computer Interface (BCI) is an efficient information detection technology by detecting event-related brain responses evoked by target visual stimuli. However, a time-consuming calibration procedure is needed before a new user can use this system. Thus, it is important to reduce calibration efforts for BCI applications.

Reducing Calibration Efforts in RSVP Tasks With Multi-Source Adversarial Domain Adaptation.

Rapid Serial Visual Presentation (RSVP)-based Brain-Computer Interface (BCI) is an efficient information detection technology by detecting event-related brain responses evoked by target visual stimuli. However, a time-consuming calibration procedure is needed before a new user can use this system. Thus, it is important to reduce calibration efforts for BCI applications.

Multi-channel EEG recording during motor imagery of different joints from the same limb.

Motor imagery (MI) is one of the important brain-computer interface (BCI) paradigms, which can be used to control peripherals without external stimulus. Imagining the movements of different joints of the same limb allows intuitive control of the outer devices. In this report, we describe an open access multi-subject dataset for MI of different joints from the same limb.

Life satisfaction in Chinese rural-to-urban migrants: Investigating the roles of self-esteem and affect balance.

The goal of the present article is to investigate whether positive and negative affects mediate or moderate the impact of self-esteem on life satisfaction among Chinese rural-to-urban migrants. Participants contained 712 rural-to-urban migrants recruited from four construction sites in China, who were evaluated with Rosenberg Self-Esteem Scale, Positive and Negative Affect Scale, and Satisfaction with Life Scale. Correlation analysis indicated self-esteem positively predicted life satisfaction.

EEG-Based Emotion Recognition with Similarity Learning Network.

Emotion recognition is an important field of research in Affective Computing (AC), and the EEG signal is one of useful signals in detecting and evaluating emotion. With the development of the deep learning, the neural network is widely used in constructing the EEG-based emotion recognition model. In this paper, we propose an effective similarity learning network, on the basis of a bidirectional long short term memory (BLSTM) network.

EEG-Based Emotion Recognition with Prototype-Based Data Representation.

Emotions play an important role in human communication, and EEG signals are widely used for emotion recognition. Despite the extensive research of EEG in recent year, it is still challenging to interpret EEG signals effectively due to the massive noises in EEG signals. In this paper, we propose an effective emotion recognition framework, which contains two main parts: the representation network and the prototype selection algorithm.

Deep Channel-Correlation Network for Motor Imagery Decoding From the Same Limb.

Motor imagery (MI) is an important brain-computer interface (BCI) paradigm, which can be applied without external stimulus. Imagining different joint movements from the same limb allows intuitive control of the outer devices. However, few researches focused on this field, and the decoding accuracy limited the applications for practical use.

Surgical medial patellofemoral ligament reconstruction versus non-surgical treatment of acute primary patellar dislocation: a prospective controlled trial.

Purpose: The acute primary (first-time) lateral patellar dislocation is associated with a high rate of functional disability. There is no consensus as to the choice of surgical or non-surgical treatment for these patients. The aim of this study is to compare the clinical results between the surgical (reconstruction of the medial patellofemoral ligament [MPFL]) and non-surgical treatments for acute primary patellar dislocations.

Improving EEG-Based Motor Imagery Classification via Spatial and Temporal Recurrent Neural Networks.

Motor imagery (MI) based Brain-Computer Interface (BCI) is an important active BCI paradigm for recognizing movement intention of severely disabled persons. There are extensive studies about MI-based intention recognition, most of which heavily rely on staged handcrafted EEG feature extraction and classifier design. For end-to-end deep learning methods, researchers encode spatial information with convolution neural networks (CNNs) from raw EEG data.