[A fluorescence immunochromatography method for detection of human papillomavirus type 16 E6 and L1 proteins].

This study aims to establish a time-resolved fluorescence immunochromatography method for simultaneous determination of human papillomavirus (HPV) type 16 E6 and L1 protein concentrations. The amount of lanthanide microsphere-labeled antibodies, the concentration of coated antibodies, and the reaction time were optimized, and then a test strip for the simultaneous determination of the protein concentrations was prepared. The performance of the detection method was evaluated based on the concordance of the results from clinical practice.

Did place-based industrial policy promote regional economic growth? ---- Evidence from China.

Whether the place-based industrial policy promotes regional economic growth is a hot issue in the field of regional industrial economic practice. As a major national strategy in China, the Beijing-Tianjin-Hebei industrial coordinated development policy has been implemented more than 8 years. Verifying its effect on regional economic growth and revealing the policy action path will help to further optimize the policy implementation process through feedback.

Source analysis of heavy metal pollution in agricultural soil irrigated with sewage in Wuqing, Tianjin.

In this study, the contents of heavy metals and Cd and Pb isotope ratios of agricultural soil and potential source samples collected from farmland receiving sewage irrigation in Wuqing District, Tianjin, China were determined. Multiple methods were used for source analysis, including positive matrix factorization (PMF), correlation analysis, principal component analysis (PCA), and the Cd and Pb isotope ratio method. The results showed that agricultural soil was slightly contaminated by heavy metals in the research area, with relatively higher Cd and Pb accumulation levels compared to those of other heavy metals.

Loss of AKR1C1 is a good prognostic factor in advanced NPC cases and increases chemosensitivity to cisplatin in NPC cells.

Cisplatin resistance is one of the main obstacles in the treatment of advanced nasopharyngeal carcinoma (NPC). AKR1C1 is a member of the Aldo-keto reductase superfamily (AKRs), which converts aldehydes and ketones to their corresponding alcohols and has been reported to be involved in chemotherapeutic resistance of multiple drugs. The expression and function of AKR1C1 in NPC have not been reported until now.

Incomplete fluid-air exchange technique for idiopathic macular hole surgery.

Aim: To explore an improved procedure involving incomplete fluid-air exchange for idiopathic macular hole (IMH), and the closure rate, visual function, and the visual field of macular holes (MHs) were evaluated.

Methods: This prospective randomized controlled study, included 40 eyes of 40 patients with IMH who were treated with pars plana vitrectomy and peeling of the internal limiting membrane. They were grouped by random digital table.

Application of artificial intelligence in ophthalmology.

Artificial intelligence is a general term that means to accomplish a task mainly by a computer, with the least human beings participation, and it is widely accepted as the invention of robots. With the development of this new technology, artificial intelligence has been one of the most influential information technology revolutions. We searched these English-language studies relative to ophthalmology published on PubMed and Springer databases.

Research progress on the role of connective tissue growth factor in fibrosis of diabetic retinopathy.

Diabetic retinopathy (DR) is one of the most important types of diabetic microangiopathy, which is a specific change of fundus lesions and is one of the most serious complications of diabetes. When DR develops to proliferative DR, the main factors of decreasing vision, and even blindness, include retinal detachment and vitreous hemorrhage caused by contraction of blood vessels by fiber membrane. Recent studies reported that the formation of fiber vascular membrane is closely related to retinal fibrosis.

Porous Coconut Shell Carbon Offering High Retention and Deep Lithiation of Sulfur for Lithium-Sulfur Batteries.

Retaining soluble polysulfides in the sulfur cathodes and allowing for deep redox are essential to develop high-performance lithium-sulfur batteries. The versatile textures and physicochemical characteristics of abundant biomass offer a great opportunity to prepare biochar materials that can enhance the performance of Li-S batteries in sustainable mode. Here, we exploit micro-/mesoporous coconut shell carbon (CSC) with high specific surface areas as a sulfur host for Li-S batteries.

Enhanced thermoelectric properties of PbBiS prepared with hydrothermal synthesis and microwave sintering.

As a cheap substitute for PbTe or PbSe, the thermoelectric performance of PbS still remains to be improved. In this report, we selected BiS as a donor and employed a facile route of hydrothermal synthesis combined with microwave sintering to fabricate BiS doped PbS. Due to the increased electrical conductivity by BiS doping and the decreased thermal conductivity from the refined microstructure, the thermoelectric figure of merit ZT of microwave sintered PbBiS and PbBiS reached 0.

Conductive Carbon Network inside a Sulfur-Impregnated Carbon Sponge: A Bioinspired High-Performance Cathode for Li-S Battery.

A highly conductive sulfur cathode is crucial for improving the kinetic performance of a Li-S battery. The encapsulation of sulfur in porous nanocarbons is expected to benefit the Li(+) migration, yet the e(-) conduction is still to be improved due to a low graphitization degree of a conventional carbon substrate, especially that pyrolyzed from carbohydrates or polymers. Aiming at facilitating the e(-) conduction in the cathode, here we propose to use ketjen black, a highly graphitized nanocarbon building block to form a conductive network for electrons in a biomass-derived, hierarchically porous carbon sponge by a easily scaled-up approach at a low cost.

Field-induced dielectric response saturation in o-TaS3.

We investigated dependence of the dielectric properties on temperature and electric field below 50 K along the chain direction of o-TaS3. With external electric field increase, two threshold features could be identified. For electric fields somewhat larger than the lower threshold [Formula: see text], the dielectric constant starts to decrease whereas the conductivity increases due to the tunnelling of solitons.

The Electrochemistry with Lithium versus Sodium of Selenium Confined To Slit Micropores in Carbon.

Substitution of selenium for sulfur in the cathode of a rechargeable battery containing Sx molecules in microporous slits in carbon allows a better characterization of the electrochemical reactions that occur. Paired with a metallic lithium anode, the Sex chains are converted to Li2Se in a single-step reaction. With a sodium anode, a sequential chemical reaction is characterized by a continuous chain shortening of Sex upon initial discharge before completing the reduction to Na2Se; on charge, the reconstituted Sex molecules retain a smaller x value than the original Sex chain molecule.

Construction and validation of a preliminary Chinese version of the Wake Forest Physician Trust Scale.

Background: The development, validation, and psychometric properties of the Wake Forest Physician Trust Scale (WFPTS)-equivalent instrument for Chinese patients were investigated.

Material And Methods: We approached 3442 randomly selected outpatients at 3 Shanghai (China) general hospitals, treated ≥2 times per year by the same physician, for participation between November 2008 and December 2008. A Chinese version of the WFPTS (C-WFPTS) was prepared and administered to eligible and consenting patients, and subjected to validity assessment using 5 patient behaviors: (1) recommendation of the physician; (2) occurrence of dispute; (3) seeking a second opinion; (4) treatment adherence; and (5) consideration of switching physicians.

[Development of multiplex microbead immunoassay for detection of specific antibodies against Cryptosporidium parvum].

Objective: To develop a multiplex microbead immunoassay for detection of specific antibodies against Cryptosporidium parvum using recombinant proteins CP23, SA35 and SA40.

Methods: By using purified recombinant proteins CP23, SA35 and SA40 as detected antigens, and bovine serum albumin (BSA) as internal control, the four proteins aforementioned were coupled with micro beads and MIA was developed. Then, the efficiency of the coupled proteins was tested, the difference between the single MIA method and the multiple MIA method was compared, and the difference between plates was also compared.

Simultaneous detection of serum immunoglobulin G antibodies to Cryptosporidium parvum by multiplex microbead immunoassay using 3 recognized specific recombinant C. parvum antigens.

Cryptosporidiosis is a significant diarrheal disease in both humans and other mammals worldwide. In the present study, we established and validated a multiplex microbead immunoassay (MIA) for surveillance of Cryptosporidium parvum infections. In the multiplex MIA, 3 specific recombinant proteins, CP23, SA35, and SA40, were used as the capture antigens simultaneously.