Publications by authors named "Xuejuan Wu"

Lens-free on-chip microscopy (LFOCM) is a powerful computational imaging technology that combines high-throughput capabilities with cost efficiency. However, in LFOCM, the phase recovered by iterative phase retrieval techniques is generally wrapped into the range of -π to π, necessitating phase unwrapping to recover absolute phase distributions. Moreover, this unwrapping process is prone to errors, particularly in areas with large phase gradients or low spatial sampling, due to the absence of reliable initial guesses.

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Lens-free on-chip microscopy is a powerful and promising high-throughput computational microscopy technique due to its unique advantage of creating high-resolution images across the full field-of-view (FOV) of the imaging sensor. Nevertheless, most current lens-free microscopy methods have been designed for imaging only two-dimensional thin samples. Lens-free on-chip tomography (LFOCT) with a uniform resolution across the entire FOV and at a subpixel level remains a critical challenge.

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Purpose: To investigate the repeatability and reproducibility of a new method for centration analysis after small incision lenticule extraction (SMILE) and femtosecond laser-assisted LASIK (FS-LASIK).

Methods: This study comprised 29 eyes treated with SMILE and 24 with FS-LASIK. Decentrations were analyzed using tangential and pachymetry difference maps respectively.

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Purpose: Whether Internet of Things (IoT)-based home respiratory muscle training (RMT) benefits patients with comorbid chronic obstructive pulmonary disease (COPD) remains unclear. Therefore, this study aims to evaluate the effectiveness of IoT-based home RMT for patients with COPD.

Patients And Methods: Seventy-eight patients with stable COPD were randomly divided into two groups.

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Oxidative stress (OS) is one of the crucial molecular events of secondary spinal cord injury (SCI). Basic fibroblast growth factor (bFGF) is a multipotent cell growth factor with an anti-oxidant effect. However, bFGF has a short half-life in vivo, which limits its therapeutic application.

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Article Synopsis
  • The SSLFPR method enables high-resolution phase imaging using a lens-free approach and LED illumination by efficiently retrieving phase information from a single diffraction pattern.* -
  • By utilizing quasi-monochromatic light components and a virtual wavelength scanning approach, the system addresses resolution loss and improves imaging quality, achieving a half-width resolution of 977 nm over a large field-of-view.* -
  • The method's ability to capture real-time images of dynamic samples, like living HeLa cells, positions SSLFPR as a promising technology for various biological and medical applications due to its simplicity and high throughput.*
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Spinal cord injury (SCI) is a devastating neurological disorder that often results in loss of motor and sensory function. Diabetes facilitates the blood-spinal cord barrier (BSCB) destruction and aggravates SCI recovery. However, the molecular mechanism underlying it is still unclear.

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We propose a lensfree on-chip microscopy approach for wide-field quantitative phase imaging (QPI) based on wavelength scanning. Unlike previous methods, we found that a relatively large-range wavelength diversity not only provides information to overcome spatial aliasing of the image sensor but also creates sufficient diffraction variations that can be used to achieve motion-free, pixel-super-resolved phase recovery. Based on an iterative phase retrieval and pixel-super-resolution technique, the proposed wavelength-scanning approach uses only eight undersampled holograms to achieve a half-pitch lateral resolution of 691 nm across a large field-of-view of 29.

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As a well-established deterministic phase retrieval approach, the transport of intensity equation (TIE) is able to recover the quantitative phase of a sample under coherent or partially coherent illumination with its through-focus intensity measurements. Nevertheless, the inherent paraxial approximation limits its validity to low-numerical-aperture imaging and slowly varying objects, precluding its application to high-resolution quantitative phase imaging (QPI). Alternatively, QPI can be achieved by phase deconvolution approaches based on the coherent contrast transfer function or partially coherent weak object transfer function (WOTF) without invoking paraxial approximation.

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By adopting PCR-RFLP and 16S rDNA sequencing, this paper analyzed the genetic diversity and phylogeny of 40 endophytic bacterial strains isolated from Caragana spp. root nodules, and determined the salt resistance, acid- and alkali resistance, and growth temperature range of the strains. A total of 9 genotypes were obtained from the 40 strains by RFLP.

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