Publications by authors named "Xuejuan Shangguan"
Article Synopsis
- Infection caused by gram-negative bacteria is a significant global health issue, contributing to high mortality rates and complications like cognitive dysfunction in survivors.
- Advances in antibiotics and medical support have improved survival, but understanding the mechanisms of infection-related complications remains limited.
- This study identifies the NLRP3 inflammasome's role in cognitive impairment following exposure to lipopolysaccharides (LPS) in mice, suggesting it as a potential target for treating cognitive dysfunction linked to infections.