Publications by authors named "Xuejia Han"
Article Synopsis
- Small molecular RNAs like microRNA (miRNA) and small interfering RNA (siRNA) are crucial in regulating gene expression, especially in cancer diagnostics and treatment.* -
- miRNAs are involved in posttranscriptional regulation, while siRNAs can silence specific genes and inhibit tumor development by targeting proto-oncogenes.* -
- Nanoparticles can protect small RNAs from degradation by RNAase, making them effective carriers for delivering these molecules in cancer therapies; the review covers their benefits, limitations, and applications.*
Danshensu methyl ester attenuated LPS-induced acute lung injury by inhibiting TLR4/NF-κB pathway.
Respir Physiol Neurobiol
April 2024
Acute Lung Injury (ALI) manifests as an acute exacerbation of pulmonary inflammation with high mortality. The potential application of Danshensu methyl ester (DME, synthesized in our lab) in ameliorating ALI has not been elucidated. Our results demonstrated that DME led to a remarkable reduction in lung injury.
View Article and Find Full Text PDFMiR-138-5p suppresses the progression of lung cancer by targeting SNIP1.
Thorac Cancer
February 2023
Background: MicroRNAs (miRNAs) play crucial roles in the development of various cancers. Here, we aimed to evaluate the roles of miR-138-5p in lung cancer progression and the value of miR-138-5p in lung cancer diagnosis.
Methods: Quantitative real-time PCR was performed to examine the expressions of miR-138-5p and smad nuclear interacting protein 1 (SNIP1) mRNA.