Newborn Screening of Genetic Mutations in Common Deafness Genes With Bloodspot-Based Gene Chip Array.

Purpose: This study screens for deafness gene mutations in newborns in the Northwest China population.

Method: The 9 sites of 4 common deafness genes (GJB2, GJB3, SLC26A4, and mt 12S rRNA) were detected by bloodspot-based gene chip array in 2,500 newborns.

Results: We detected mutations of the 4 genes in 101 (4.