Antitumor activity of Portulaca oleracea L. polysaccharides against cervical carcinoma in vitro and in vivo.

Portulaca oleracea L. has been used as folk medicine in different countries to treat different ailments in humans. P.

Effects of matrine on HepG2 cell proliferation and expression of tumor relevant proteins in vitro.

Matrine, one of the main active components extracted from dry roots of Sophora flavescens Ait (Leguminosae), has been reported to have anticancer effects on a number of cancer cell lines, but the anticancer mechanism of matrine remains elusive. This study shows that matrine also displays anticancer activity on human hepatocellular carcinoma (HepG2) cells. In this work, the optimal cultivation condition for HepG2 cells was determined using the combinatorial orthogonal test design [L18 (21 x 37)].

[Effects of oxymatrine on proliferation of HepG2 cells].

Objective: To investigate the effects and the mechanisms on oxymatrine inhibiting proliferation of HepG2 cells.

Method: HepG2 cells were exposured to oxymatrine, final concentrations of which were 0.1, 0.