Publications by authors named "Xuefeng Kuang"
Article Synopsis
- The study followed 3,681 healthy women aged 18-45 for over 5 years to investigate HR-HPV infections and their outcomes, using regular cervical testing and colposcopy for abnormal results.
- Data indicated that younger women (18-26 years) had a higher incidence of persistent HR-HPV infections and cervical lesions (CIN2+) than mid-adult women (27-45 years), suggesting age-related differences in risk.
- Despite lower rates of infection and lesions in mid-adult women, they still face a significant risk of acquiring HR-HPV infections that could lead to cervical issues, highlighting the need for continued monitoring.
To assess the pattern of multiple human papillomavirus infection to predict the type replacement postvaccination. A total of 7372 women aged 18-45y from a phase III trial of an -produced HPV-16/18 vaccine were analyzed at enrollment visit before vaccination. Hierarchical multilevel logistic regression was used to evaluate HPV vaccine type and nonvaccine-type interactions with age as a covariate.
View Article and Find Full Text PDFMitochondrial fission depends on dynamin-related protein 1 (Drp1) guanosine triphosphatase activity. Although there is some association between Drp1 and gastric cancer, the detailed mechanism remains largely unknown. In this study, the elevation of Drp1 was observed in human gastric carcinoma specimens including gastric mixed adenocarcinoma tissues, gastric intestinal-type adenocarcinoma tissues, and human gastric cancer cells compared to normal control, but not in diffuse gastric adenocarcinoma tissues.
View Article and Find Full Text PDFBackground: Immunosuppressive receptor LILRB1 regulates tumors progression by transducing immune inhibitory signals via intracellular immunoreceptor tyrosine-based inhibitory motifs. However, its role in Hepatocellular Carcinoma (HCC) remains vague.
Objective: This study is aimed to disclose the association between LILRB1 and HCC.