Therapeutic prospect on umbilical cord mesenchymal stem cells in animal model with primary ovarian insufficiency: a meta-analysis.

Background: Primary ovarian insufficiency (POI) leads to not only infertile but several adverse health events to women. Traditional treatment methods have their own set of limitations and drawbacks that vary in degree. Application of human umbilical cord mesenchymal stem cell (hUCMSC) is a promising strategy for POI.

Clinical effectiveness and potential long-term benefits of high-intensity focused ultrasound therapy for patients with adenomyosis.

Objectives: Adenomyosis is a common and refractory disease in gynecology. Preserving the uterus during treatment for adenomyosis remains a problem. High-intensity focused ultrasound (HIFU) is widely used in treatment of solid tumors.

A case report of primary multiple obturator nerve schwannomas.

Primary multiple obturator nerve schwannomas originate from Schwann cells and are extremely rare. Patients with schwannomas are asymptomatic and a retroperitoneal schwannoma is often misdiagnosed as an adnexal mass. In the present study, we describe a 58-year-old woman in whom a right adnexal mass accompanied by endometrial polyp was found incidentally through transvaginal ultrasound.

Therapeutic Effect of Human Amniotic Epithelial Cells in Rat Models of Intrauterine Adhesions.

As a refractory fibrosis disease, intrauterine adhesions (IUAs) is defined as fibrosis of the physiological endometrium. Although hysteroscopic adhesiolysis is widely recommended as an effective treatment, prognosis and recurrence remain poor in severe cases. Recently, stem cell therapy has been promoted as a promising treatment for IUAs.

A Case Report Of Uterine Leiomyosarcoma.

Background: Uterine leiomyoma is the most common benign tumor in women. Uterine sarcoma, though with very low incidence, has a high malignant degree and poor prognosis. It has difficulties in preoperative diagnosis, frozen pathological examination and postoperative treatment.

Mechanisms of endometrial fibrosis and the potential application of stem cell therapy.

Fibrosis diseases result from excessive accumulation of extracellular matrix proteins which lead to normal tissue being replaced by fibrotic tissue or scar and eventually cause organ failure. Endometrial fibrosis is defined as the physiological endometrium becoming fibrosed, also known as intrauterine adhesions (IUA) or Asherman's syndrome, which progressively impairs endometrial function. On the basis of the fibrosis pathology, prevention of endometrial fibrosis is fundamental for IUA treatment, and elucidating the cellular and molecular mechanisms underlying endometrial fibrosis is imperative.