Pancreatic cancer-associated diabetes mellitus is characterized by reduced β-cell secretory capacity, rather than insulin resistance.

Aims: The early distinction of pancreatic cancer associated diabetes (PaCDM) in patients with elderly diabetes is critical. However, PaCDM and type 2 diabetes mellitus (T2DM) remain indistinguishable. We aim to address the differences between the pancreatic and gut endocrine hormones of patients with PaCDM and T2DM.

Serum REG Iα as a potential novel biomarker in cancer: An observational study.

The regulation of the gene-regenerating family member 1 alpha (REG Iα) played important roles in cancer cell biology. However, the correlation between its gene product serum REG Iα and cancer has not been evaluated. In this observational study, 130 hospitalized patients from the department of internal medicine in Zhongda Hospital Southeast University were included and assigned to cancer or noncancer groups.

Association between lipoprotein-associated phospholipase A and lower extremity arterial disease in type 2 diabetes mellitus.

Background: Lipoprotein-associated phospholipase A (Lp-PLA) is closely related to the development of cardiovascular diseases, and the association between Lp-PLA and lower extremity arterial disease (LEAD) in type 2 diabetes mellitus (T2DM) is inconsistent among previous studies. Thus, the present study aimed to investigate whether the increase in Lp-PLA is related to the occurrence of LEAD in patients with T2DM.

Methods: A total of 519 patients with T2DM (173 patients with LEAD and 346 patients without LEAD) were enrolled in this study.