Publications by authors named "Xuebin Wen"
Gliomas are malignant tumors of the central nervous system; current treatment methods have low efficacy. Twisted gastrulation BMP signaling modulator 1 (TWSG1) has been shown to play a role in gliomas but it is not known whether TWSG1 participates in glioma pathogenesis and macrophage immune regulation. This study identified a total of 24 differentially expressed genes with survival differences in gliomas using bioinformatics analysis.
View Article and Find Full Text PDFObjective: Numerous studies have posited the involvement of serum uric acid (SUA) in the pathogenesis and progression of various cardiovascular diseases, particularly aortic aneurysms. However, the casual effect of SUA level on intracranial aneurysms (IAs) was rarely studied. Consequently, we aimed to explore the causal association between SUA and IAs using Mendelian randomization (MR) analysis.
View Article and Find Full Text PDFThis study aimed to evaluate the potential of cluster of differentiation 86 (CD86) as a biomarker in high-grade glioma (HGG). The TCGA and TCIA databases were used to obtain the CD86 expression value, clinical data, and MRI images of HGG patients. Prognostic values were assessed by the Kaplan-Meier method, Receiver operating characteristic curve (ROC), Cox regression, logistic regression, and nomogram analyses.
View Article and Find Full Text PDFArticle Synopsis
- The study compares two mechanical thrombectomy techniques—contact aspiration (CA) and stent retriever (SR)—for treating acute ischemic strokes caused by M2 segment occlusions in the middle cerebral artery.
- A systematic review found no significant difference in the effectiveness of CA and SR on final successful reperfusion and 90-day functional independence, with both techniques yielding similar outcomes based on various studies.
- The authors conclude that while both methods appear equally effective, more randomized controlled trials are necessary to further evaluate and confirm these findings.
Article Synopsis
- - The meta-analysis compared the effectiveness of two treatments, stent retriever (SR) and contact aspiration (CA), for acute posterior circulation strokes (PCS) based on recent studies.
- - Results showed that first-line CA had significantly better outcomes, including higher rates of successful blood flow restoration (mTICI scores), fewer complications, and shorter procedure times compared to SR.
- - Patients treated with CA also experienced better functional independence and lower mortality at the 90-day follow-up, suggesting CA might be a more effective first-line treatment for acute PCS, although the quality of the studies analyzed was a limitation.
[Current situation and countermeasures of medical damage risk sharing system in China].
Zhong Nan Da Xue Xue Bao Yi Xue Ban
January 2015
Although medical damage risks really exist, an effective medical risk sharing system is still not available in China right now. By analyzing the status quo of Chinese medical damage risks sharing system, the authors put forward the following suggestions to improve the current system: Upgrading the preventive strategy for medical disputes, establishing multi-level and multi-channel comprehensive medical damage risks sharing system, promoting the effective cooperation between insurance relief systems and mediation system for medical disputes, and constructing highly effective pathways to resolve the medical disputes.
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