Impact of diverse exogenous hormones on parthenocarpy, yield, and quality of pepino () in the Qinghai-Tibet plateau's natural conditions.

Unlabelled: Pepino (), native to the Andes Mountains, requires exogenous hormones in its brief frost-free plateau environment to induce parthenocarpy and ensure yield.The effects of different plant growth regulators and application methods on pepino's growth, yield, and fruit quality were analyzed. Results showed that exogenous plant growth regulators had significant effects on various plant traits For instance, plant height decreased by 43.

Heat dissipation analysis and multi-objective optimization of microchannel liquid cooled plate lithium battery pack.

An efficient battery pack-level thermal management system was crucial to ensuring the safe driving of electric vehicles. To address the challenges posed by insufficient heat dissipation in traditional liquid cooled plate battery packs and the associated high system energy consumption. This study proposes three distinct channel liquid cooling systems for square battery modules, and compares and analyzes their heat dissipation performance to ensure battery safety during high-rate discharge.

Biomimetic superparamagnetic gelatin/chitosan asymmetric fibrous membrane for accelerating wound healing under static magnetic field.

The single structure, poor mechanical properties, and low biological activity of wound dressings usually lead to unsatisfactory treatment effects. Gelatin and chitosan possess excellent biofunction, but they lack sufficient mechanical support. Magnetic biomaterials and magnetic fields have shown surprising tissue repair potential.

Tinglu Yixin granule inhibited fibroblast-myofibroblast transdifferentiation to ameliorate myocardial fibrosis in diabetic mice.

Ethnopharmacological Relevance: Myocardial fibrosis is one of the pathological characteristics of advanced diabetic cardiomyopathy (DCM) and serves as the strong evidence of poor prognosis. Among them, the transdifferentiation of cardiac fibroblasts (CFs) may play a crucial role in the development of myocardial fibrosis in DCM. Tinglu Yixin granule (TLYXG) has been clinically used for many years and can significantly improve cardiac function of patients with DCM.

Development and validation of knowledge, attitude, and practice scale regarding antibiotic use for Chinese medical students.

Aims And Objectives: This study aimed to develop and validate a knowledge, attitude, and practice scale of antibiotic use for Chinese medical students.

Method: A five-phased procedure was adopted: (a) A item pool was constructed after literature review; (b) Delphi method was used to refine the items; (c) A pilot study was conducted to clarify the item; (d) Item analysis and exploratory factor analysis were used to finalize the scale; (e) Content validity, construct validity and reliability of the scale were analysed.

Results: The scale of 32 items, respectively 15, 9, and 8 for knowledge, attitude, and practice, was finalized.

Elucidating the role of 4-hydroxy-2(3H)-benzoxazolone in chronic alcoholic liver disease via transcriptomics and metabolomics.

Background: Chronic alcoholic liver disease (CALD) is a global health problem which includes multiple pathological processes such as immune inflammation and oxidative stress. 4-hydroxy-2(3H)-benzoxazolone (HBOA), an alkaloid isolated from L, has been shown to exert hepatoprotective and immunomodulatory effects. However, its effects on CALD remain unclear.

Fast-response fiber organic electrochemical transistor with vertical channel design for electrophysiological monitoring.

Fiber organic electrochemical transistors (OECTs) hold significant promise for bio-signal amplification due to their minimally invasive and seamless integration with biological tissues. However, their use in monitoring rapid physiological changes, such as electrophysiological signals, has been constrained by slow response time, arising from their extensive channel dimensions. Here, we introduce a novel fiber OECT designed with a micro-scale vertical channel (F-vOECT) that substantially reduces the response time by an order of magnitude to 12 ms and achieves a maximum transconductance of 16 mS at zero gate bias, marking a substantial improvement over previous fiber OECTs.

Impact of early caffeine administration on respiratory outcomes in very preterm infants initially receiving invasive mechanical ventilation.

Objective: The guidelines recommend early caffeine administration for preterm infants requiring non-invasive mechanical ventilation since earlier treatment is associated with better outcomes. The objective was to evaluate the impact of early caffeine therapy (within 24 hours after birth) on respiratory outcomes in very preterm infants who were initially receiving invasive mechanical ventilation.

Methods: This was an observation cohort study from 1 January 2018 to 31 December 2022 based on a database that was prospectively collected and maintained.

Expression and pathogenesis of insulin-like growth factor-1 and insulin-like growth factor binding protein 3 in a mouse model of ulcerative colitis.

Background And Aim: Insulin-like growth factor-1 may be involved in the epithelial-to-mesenchymal transition process. It can mitigate adverse effects when interacting with insulin-like growth factor binding protein 3. This study aimed to explore alterations in the expression of these two factors in the colonic tissue of mice with ulcerative colitis.

Comprehensive analysis of diagnosis and treatment in 99 cases of abdominal Schwannoma.

Purpose: Schwannoma is a rare mesenchymal tumor. In this study, we analyzed clinicopathologically 99 schwannomas.This retrospective study delves into the clinical, pathological, and immunohistochemical dimensions of abdominal schwannomas.

All-Metal Flexible Fiber by Continuously Assembling Nanowires for High Electrical Conductivity.

Fiber electronics booms as a new important field but is currently limited by the challenge of finding both highly flexible and conductive fiber electrodes. Here, all-metal fibers based on nanowires are discovered. Silver nanowires are continuously assembled into robust fibers by salt-induced aggregation and then firmly stabilized by plasmonic welding.

forming ultra-mechanically sensitive materials for high-sensitivity stretchable fiber strain sensors.

Fiber electronics with flexible and weavable features can be easily integrated into textiles for wearable applications. However, due to small sizes and curved surfaces of fiber materials, it remains challenging to load robust active layers, thus hindering production of high-sensitivity fiber strain sensors. Herein, functional sensing materials are firmly anchored on the fiber surface through a hydrolytic condensation process.

Combined toxicity of polyvinyl chloride microplastics and copper to marine jacopever (Sebastes schlegelii).

Marine organisms commonly encounter co-stress resulting from the coexistence of microplastics (MPs) and heavy metals pollution in marine environments. Nevertheless, the combined effects and toxicity mechanisms of MPs and heavy metals on marine organisms remain unclear. This study integrated growth, physiological, morphological, and biochemical markers to assess the individual and combined toxicity of polyvinyl chloride MPs (PVC MPs, 1 × 10 particles/L) and copper (Cu, 200 μg/L) on marine jacopever (Sebastes schlegelii).

High-performing fiber electrodes based on a gold-shelled silver nanowire framework for bioelectronics.

Flexible fiber electrodes offer new opportunities for bioelectronics and are reliable applications, high flexibility, high electrical conductivity, and satisfactory biocompatibility are typically required. Herein, we present an all-metal flexible and biocompatible fiber electrode based on a metal nanowire hybrid strategy, , silver nanowires were assembled on a freestanding framework, and further to render them inert, they were plated with a gold nanoshell. Our fiber electrodes exhibited a low modulus of ∼75 MPa and electrical conductivity up to ∼4.

Bioaccumulation of polycyclic aromatic hydrocarbons and their human health risks depend on the characteristics of microplastics in marine organisms of Sanggou Bay, China.

Microplastics pose a threat to marine environments through their physical presence and as vectors of chemical pollutants. However, the impact of microplastics on the accumulation and human health risk of chemical pollutants in marine organisms remains largely unknown. In this study, we investigated the microplastics and polycyclic aromatic hydrocarbons (PAHs) pollution in marine organisms from Sanggou Bay and analyzed their correlations.

PVP/aprepitant microcapsules produced by supercritical antisolvent process.

The supercritical antisolvent (SAS) process was a green alternative to improve the low bioavailability of insoluble drugs. However, it is difficult for SAS process to industrialize with limited production capacity. A coaxial annular nozzle was used to prepare the microcapsules of aprepitant (APR) and polyvinylpyrrolidone (PVP) by SAS with N, N-Dimethylformamide (DMF) as solvent.

Interaction of physical activity and low-level air pollution on cardiovascular disease: a prospective cohort study in UK Biobank.

To investigate the associations of physical activity (PA), low-level air pollution, and interaction on cardiovascular diseases (CVD) incidence based on the UK Biobank. PA was measured by the International Physical Activity Questionnaire and five air pollutants were estimated using Land Use Regression. All association estimates were based on Cox regression.

High-performance fibre battery with polymer gel electrolyte.

Replacement of liquid electrolytes with polymer gel electrolytes is recognized as a general and effective way of solving safety problems and achieving high flexibility in wearable batteries. However, the poor interface between polymer gel electrolyte and electrode, caused by insufficient wetting, produces much poorer electrochemical properties, especially during the deformation of the battery. Here we report a strategy for designing channel structures in electrodes to incorporate polymer gel electrolytes and to form intimate and stable interfaces for high-performance wearable batteries.

Development and Validation of Knowledge Assessment Scales for Dementia and Urinary Incontinence in Community Older People.

To develop and validate scales for reliably assessing dementia and urinary incontinence knowledge of older adults in the community. Items were generated through a literature review, refined through a Delphi study ( = 19), and then revised through a pilot study ( = 29). Item analysis and exploratory factor analysis were applied to finalize the scales ( = 244).

Increasing the Amounts of Bioactive Components in American Ginseng ( L.) Leaves Using Far-Infrared Irradiation.

Both the roots and leaves of American ginseng contain ginsenosides and polyphenols. The impact of thermal processing on enhancing the biological activities of the root by altering its component composition has been widely reported. However, the effects of far-infrared irradiation (FIR), an efficient heat treatment method, on the bioactive components of the leaves remain to be elucidated.