A randomized controlled trial of an intervention for unmet supportive care needs addressing colorectal cancer couples.

Purpose: Supported by the Supportive Care Needs Framework (SCNF), we developed a colorectal cancer (CRC) couple-based unmet supportive care needs (USCNs) intervention program, which has been proven to be feasible. The intention was to assess what the clinical efficacy of this intervention would be in CRC couples.

Methods: One hundred and sixty-eight CRC couples were randomly assigned to one of two groups: a control group (receiving normal care) or an intervention group (receiving normal care plus a five-week USCNs intervention).

Spatial Distribution and Dietary Risk Assessment of Aflatoxins in Raw Milk and Dairy Feedstuff Samples from Different Climate Zones in China.

This study aimed to explore the contamination of aflatoxins by investigating the spatial distribution of aflatoxin B1 (AFB1) in cow feedstuff and aflatoxin M1 (AFM1) in raw milk, and the potential health risks of AFM1 in milk and dairy products. Feedstuff and raw milk were collected from 160 pastures in three climate zones of China from October to November 2020. The results indicated the level of AFB1 and AFM1 ranged from 51.

Association of steatotic liver disease with all-cause and cardiovascular mortality among prehypertensive or hypertensive patients.

Background: Prehypertension and hypertension often coexist with non-alcoholic fatty liver disease (NAFLD) during the progression of cardiovascular disease (CVD). International academic liver societies have recently reached a consensus to replace NAFLD with the new term 'steatotic liver disease' (SLD). In this study, we aimed to evaluate the impact of different SLD subtypes on all-cause and CVD mortality in individuals with prehypertension or hypertension.

In situ decoration of AuPd nanoparticles on MOF derived ZnO for ultra-high response and low detection limit trimethylamine detection.

Background: Trimethylamine (TMA) is a colorless, volatile gas with a strong irritating odor. Prolonged exposure to a certain amount of TMA can cause symptoms such as dizziness, nausea and difficulty breathing, and may even be life-threatening. Therefore, effective detection of TMA is crucial.

Impact of urban trees on carbon dioxide exchange: Mechanistic pathways, environmental controls, and feedback.

The increase of carbon dioxide (CO) concentration in the atmosphere is held responsible for global climate changes. To meet the objective of achieving carbon neutrality and keeping global warming in check, many cities, as hotspots of CO emissions, have been promoting the use of urban greenery, urban trees in particular, to mitigate carbon emissions from the built environment. However, there remain large uncertainty and divergence of the potential of urban trees for carbon mitigation, with the underlying mechanisms poorly understood.

Assessment of photoreceptor recovery and visual function utilizing adaptive optics and microperimetry in patients with surgically closed macular holes.

Background: This study investigated the association between photoreceptor structural restoration and visual function outcomes in patients undergoing surgery for closed macular holes (MHs). Using adaptive optics scanning laser ophthalmoscopy (AOSLO) and microperimetry, we aimed to provide a more detailed understanding of photoreceptor recovery and visual improvement in closed MHs.

Methods: We conducted a retrospective observational study of 31 eyes of 28 patients who underwent vitrectomy with internal limiting membrane (ILM) peeling to treat idiopathic MHs.

The congruence and interrelationships of family resilience in couples coping with colorectal cancer: A cross-sectional study from a dyadic perspective.

Purpose: To assess the congruence and interdependent impacts of family resilience in colorectal cancer couples using the Walsh Family Resilience Model, focusing on coping domains of the shared beliefs system, organizational patterns, and communication/problem-solving.

Methods: 220 colorectal cancer couples were recruited from two hospitals in China, assessing family resilience, hope, family sense of coherence, spiritual well-being, social support, and couple communication quality. Congruence was assessed using intraclass correlation coefficients and paired t-tests.

Effects of PM components on hypertension and diabetes: Assessing the mitigating influence of green spaces.

Background: Particulate matter with diameters ≤2.5 μm (PM) is a significant air pollutant associated with hypertension and diabetes. However, the specific contributions of its components and their joint exposure with green spaces remain poorly understood, especially in developing regions.

Vitrectomy Combined with Internal Limiting Membrane Peeling for the Treatment of Hemorrhagic Retinal Arterial Macroaneurysm with "Multilayered" Hemorrhages.

Aims: To report clinical outcomes of pars plana vitrectomy combined with internal limiting membrane (ILM) peeling in the treatment of "multilayered" hemorrhages caused by hemorrhagic retinal arterial microaneurysm (RAM) in three cases.

Methods: Three patients with hemorrhagic RAM were reviewed. All patients underwent vitrectomy combined with ILM peeling.

In-Device Ballistic-Electron-Emission Spectroscopy for Accurately In Situ Mapping Energy Level Alignment at Metal-Organic Semiconductors Interface.

Energy level alignment at metal/organic semiconductors (OSCs) interface governs electronic processes in organic electronics devices, making its precise determination essential for understanding carrier transport behaviors and optimizing device performance. However, it is proven that accurately characterizing the energy barrier at metal/OSC interface under operational conditions remains challenging due to the technical limitations of traditional methods. Herein, through integrating highly-improved device constructions with an ingenious derivative-assisted data processing method, this study demonstrates an in-device ballistic-electron-emission spectroscopy using hot-electron transistors to accurately characterize the energy barrier at metal/OSC interface under in-operando conditions.

Family Resilience and Its Influencing Factors in Patients With Cancer and Their Family Members: A Systematic Review.

Aims: This review aims to explore factors influencing family resilience in families providing care for patients with cancer and to provide suggestions for future research directions.

Methods: Six electronic databases were searched including Web of Science, CINAHL, EMBASE, PsycINFO, PubMed and CNKI from their inception to December 2023. The article reference lists were also manually searched.

Halogenated-edge polymeric semiconductor for efficient spin transport.

Organic semiconductors (OSCs) are featured by weak spin-orbit coupling due to their light chemical element composition, which enables them to maintain spin orientation for a long spin lifetime and show significant potential in room-temperature spin transport. Carrier mobility and spin lifetime are the two main factors of the spin transport performance of OSCs, however, their ambiguous mechanisms with molecular structure make the development of spintronic materials really stagnant. Herein, the effects of halogen substitution in bay-annulated indigo-based polymers on carrier mobility and spin relaxation have been systematically investigated.

Shiitake mushroom-derived extracellular nanovesicles: Preparation, characterization, and inhibition of Caco-2 cells.

In this study, Shiitake mushroom-derived extracellular nanovesicles (SMDENVs) were isolated from fresh Shiitake mushrooms by ultracentrifugation and sucrose gradient ultracentrifugation. The morphological characteristics of SMDENVs were investigated via Transmission Electron Microscopy and Laser Scanning Confocal Microscopy. SMDENVs were spherical, hollow, and uniform in size, with an average diameter of 177.

Bisphenol mixtures, metal mixtures and type 2 diabetes mellitus: Insights from metabolite profiling.

Background: Little is known about the combined effect of bisphenol mixtures and metal mixtures on type 2 diabetes mellitus (T2DM) risk, and the mediating roles of metabolites.

Methods: The study included 606 pairs of T2DM cases and controls matched by age and sex, and information of participants was collected through questionnaires and laboratory tests. Serum bisphenol and plasma metal concentrations were measured using ultra-performance liquid chromatography-mass spectrometry (UPLC-MS/MS) and inductively coupled plasma-mass spectrometry (ICP-MS), respectively.

Discordant High Remnant Cholesterol With LDL-C Increases the Risk of Stroke: A Chinese Prospective Cohort Study.

Background: Previous studies focusing on assessing the effects of remnant cholesterol (RC) and low-density lipoprotein cholesterol (LDL-C) on stroke may not consider their mutual influence. We aimed to explore the associations of RC and discordant high RC with LDL-C with stroke, ischemic stroke (IS), and hemorrhagic stroke.

Methods: This prospective cohort study was conducted based on 3 cohorts of the China-PAR (Prediction for Atherosclerotic Cardiovascular Disease Risk in China) project.

Exploring the relationship between infectious agents and autoimmune diseases: a review.

The relationship between infectious agents and autoimmune diseases is a complex issue. In recent years, increasing clinical cases have indicated that infectious agents play an important role in the development of autoimmune diseases. Molecular mimicry is currently widely regarded as the primary pathogenic mechanism of various autoimmune diseases in humans.

Effects of PM and high-fat diet on glucose and lipid metabolisms and role of MT-COX3 methylation in male rats.

Both fine particulate matter (PM) and high-fat diet (HFD) can cause changes in glucose and lipid metabolisms; however, the mechanism of their combined effects on glucose and lipid metabolisms is still unclear. This study aimed to investigate the effects of PM and HFD co-exposure on glucose and lipid metabolisms and mitochondrial DNA methylation in Wistar rats. PM and HFD co-treatment led to an increase in fasting blood glucose levels, an alteration in glucose tolerance, and a decrease in high density lipoprotein cholesterol (HDL-C) levels in Wistar rats.

Sources, trigger points, and effect size of associations between PM-bound polycyclic aromatic hydrocarbons (PAHs) and fractional exhaled nitric oxide (FeNO): A panel study with 16 follow-up visits over 4 years.

Exposure to fine particulate matter (PM) is a significant concern for respiratory health. However, the sources, trigger points, and effect size of specific associations between PM components, particularly polycyclic aromatic hydrocarbons (PAHs) and the airway inflammatory marker fractional exhaled nitric oxide (FeNO) have not been fully explored. In this study, 69 healthy college students were enrolled and followed up 16 times from 2014 to 2018.

A couple-based unmet supportive care needs intervention for colorectal cancer couples: A preliminary feasibility study.

Purpose: To support colorectal cancer couples cope with cancer, we developed a couple-based unmet supportive care needs intervention program guided by the Supportive Care Needs Framework and examined the feasibility, acceptability, and initial effects of the unmet supportive care needs program.

Methods: The design of a pre-and post-intervention study was conducted among Chinese colorectal cancer couples. The intervention was delivered in five sessions through in-person and telephone interventions combined.

Factors Influencing Social Isolation among Cancer Patients: A Systematic Review.

(1) Background: Social isolation, which has numerous adverse effects on health status, is prevalent among cancer patients. This review proposes to identify the influencing factors of social isolation among cancer patients. (2) Methods: Articles published in English or Chinese from six electronic databases before December 2023 were identified via a systematic search.

Association between urinary arsenic species and vitamin D deficiency: a cross-sectional study in Chinese pregnant women.

Background: An increasing number of studies suggest that environmental pollution may increase the risk of vitamin D deficiency (VDD). However, less is known about arsenic (As) exposure and VDD, particularly in Chinese pregnant women.

Objectives: This study examines the correlations of different urinary As species with serum 25 (OH) D and VDD prevalence.