Publications by authors named "Xue-lu Xiao"
[Study on the surface markers on peripheral blood dendritic cells and their secretion of IL-12 and IFN-alpha in SLE patients].
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi
July 2005
Article Synopsis
- The study aims to investigate surface markers on dendritic cells (DCs) in patients with systemic lupus erythematosus (SLE) and their role in the disease's development.
- By separating peripheral blood mononuclear cells (PBMCs) and stimulating DCs with specific cytokines, researchers analyzed various surface markers and cytokine levels through flow cytometry and ELISA.
- Findings show that certain surface markers were significantly higher in SLE patients compared to normal subjects, suggesting that DCs may contribute to SLE pathogenesis through enhanced antigen presentation and IL-12 secretion.