Epidemiological characteristics and pathological changes of primary glomerular diseases.

Objective: By analyzing the pathological characteristics and clinical data of renal biopsy in our hospital in the past 20 years, to further understand the epidemic characteristics and pathological changes of primary glomerular disease, and to provide regional data for the big data of kidney disease in my country.

Methods: A retrospective analysis of 9448 patients with primary glomerular disease who were hospitalized in our hospital from January 1, 2000 to December 31, 2019, aged 18 years or older, and undergoing renal biopsy. Divided every 5 years into a group, a total of 4 groups (first group 2000.

[Recurrent N1173K mutation in FBN1 gene in a Chinese family with ectopia lentis].

Objective: To study the disease-causing gene mutation in a Chinese family with ectopia lentis.

Methods: The phenotype of each family member in a Chinese family with ectopia lentis was identified by detailed clinical examination. The inheritance mode in this family was ascertained by the pedigree analysis.