Vitrectomy for Complicated Retinal Detachment Without the Use of Perfluorocarbon Liquid: A Real-World Data and Retrospective Study.

Introduction: This study aimed to evaluate the effectiveness of vitrectomy without using perfluorocarbon liquid (PFCL) for the treatment of complicated retinal detachment (RD).

Methods: The utilisation of PFCL was calculated in four hospitals in 2020 and in one hospital every year from 2012 to 2020. A case series of 320 RD eyes treated with vitrectomy without the use of perfluorocarbon liquid (VWTPL) was followed up for 1-26 months.

Decreased expression of TIPE2 in the eye under high-glucose conditions tested in vivo and in vitro.

Aims: Inflammation is important in the development of angiogenesis diabetic retinopathy (DR). Anti-inflammation is promising strategy in early DR management. This study aimed to evaluate the level of tumour necrosis factor (TNF)-α-induced protein-8 like-2 (TIPE2), a formerly anti-inflammatory factor, under high-glucose conditions.

Anti-inflammatory TIPE2 inhibits angiogenic VEGF in retinal pigment epithelium.

Choroidal neovascularization (CNV) is a pathological feature which commonly occurs in ocular diseases. This condition is characterised by vasculogenesis and angiogenesis underlying the neuroretina, with retinal pigment epithelium (RPE) and choroid as main targets. Inflammation and immunity are crucial in the early development of CNV.

Retinal vein occlusion in retinal racemose hemangioma: a case report and literature review of ocular complications in this rare retinal vascular disorder.

Backgroud: Retinal racemose hemangioma (RRH) is a rare congenital disorder that often co-occurs with other ocular complications. In this study, we present a case of RRH complicated with retinal vein obstruction in three branches and provide a review of ocular complications and associations with RRH.

Case Presentation: One case of RRH is presented.

Low-dose strontium-90 irradiation is effective in preventing the recurrence of pterygia: a ten-year study.

Background: To study the long-term effects of low-dosage strontium-90 (Sr90) irradiation on the recurrence of pterygium.

Methodology/principal Findings: One hundred twenty eyes from 104 patients with primary or recurrent pterygia were treated with surgery followed by Sr90 irradiation. In brief, starting on the sixth day after surgery, patients were treated with irradiation three times every other day at a total combined dosage of 2000 cGy to 3000 cGy.

[Founder effect of two families with TGFBI related Thiel-Behnke corneal dystrophy].

Objective: To investigate the transforming growth factor beta induced (TGFBI; BIGH3) gene mutation and founder effect of two large Chinese families clinically diagnosed as Thiel-Behnke corneal dystrophy.

Methods: Fifteen members including 13 affected and 2 healthy in family A, 14 members including 6 affected and 8 healthy in family B, as well as 20 other unrelated healthy individuals were tested for TGFBI gene mutation. Haplotype analysis and clinical examination were also carried out in the two families.

Anisometropia is independently associated with both spherical and cylindrical ametropia.

Purpose: To explore the associations between anisometropia and spherical ametropia, astigmatism, age, and sex.

Method: Associations between the prevalence and magnitude of anisometropia with age, sex, spherical power, and cylindrical power, were assessed in a group of 90,884 subjects attending optometry practices in the United Kingdom. Logistic regression models were used to assess the independent contribution of each explanatory variable.

Postnatal refractive development in the Brown Norway rat: limitations of standard refractive and ocular component dimension measurement techniques.

Purpose: The genetic tractability of the rat and its larger eye size as compared to the mouse make it an attractive model for studies of ocular development and emmetropisation. This study aimed to provide normative data in the strain of rat being used for the rat genome sequencing project whilst also evaluating standard measurement techniques.

Methods: Ocular refraction (retinoscopy, Hartinger coincidence optometry) and ocular component dimensions (keratometry, A-scan ultrasonography, calliper measures, eye weight) were measured at intervals from eye-opening to adulthood.

[The recovery of binocular vision in the early post-operative stage of senile cataract patient].

Objective: To study the recovery of binocular vision and the risk factors that affect the recovery in the early post-operative stage of senile cataract patients.

Methods: Patients undergone extracapsular cataract extraction with intraocular lens implantation (ECCE group) or cataract phacoemulsification with intraocular lens implantation (PHACO group) were examined for their corrected visual acuity, refractive power, simultaneous perception, fusion, near and far-distance stereoacuity.

Results: Before operation, the visual acuity was worse in the ECCE group than that in the PHACO group (chi(2) = 9.