Enantioselective Synthesis of 2,3,3a,8a-Tetrahydrofuro[2,3-]benzofuran Scaffolds Enabled by Cu(II)/SPDO-Catalyzed [3+2] Cycloaddition of 2,3-Dihydrofuran and Quinone Esters.

An asymmetric [3+2] cycloaddition of quinone esters with 2,3-dihydrofuran has been realized via a newly developed Cu(II)/SPDO complex. It provides straightforward access to 2,3,3a,8a-tetrahydrofuro[2,3-]benzofurans (TFB) with high enantioselectivity (up to 97.5:2.

[Retraction Note: Association of Gene Polymorphisms in Wnt Signal Pathway with Tuberculosis in Chinese Tibetan Population.2016,47(6):920-925.].

This corrects the article DOI: 10.13464/j.scuxbyxb.

[Methylation Chip Screening and Verification of Differential Genes Related to Tuberculosis Infection].

Objective: To screen the genes with significant changes in DNA methylation level in active tuberculosis patients, we used the methylation chips and expanded the sample size to verify candidate genes.

Methods: ① This study enrolled 9 cases of active tuberculosis patients, 3 cases of latent tuberculosis patients and 3 cases of healthy controls whose age and gender were all matched. Genome DNA was extracted from peripheral blood mononuclear cell in blood samples collected from these candidates, and bisulfite conversion treatment was then conducted.

[Methylation Analysis and Validation of Whole Genome DNA in Active Tuberculosis].

Objective: To screen and identify the gene of DNA methylation in patients with active tuberculosis.

Methods: ① This study enrolled 9 cases of active tuberculosis patients (including 3 newly diagnosed tuberculosis patients and 6 cases of retreatment of active tuberculosis patients), 3 cases of latent tuberculosis patients and 3 cases of healthy controls. Genome DNA was extracted from Peripheral Blood Mononuclear Cell and following bisulfite conversion treatment.

[Association of Gene Polymorphisms in Wnt Signal Pathway with Tuberculosis in Chinese Tibetan Population.].

Objectives: To determine the correlation between gene polymorphisms in Wnt signal pathway and susceptibility of Chinese Tibetan people to tuberculosis.

Methods: A total of 488 active tuberculosis patients and 454 healthy subjects(control) were enrolled in this case-control study.Five single nucleotide polymorphisms (SNPs) in Wnt signal pathway (rs4135385 in gene,rs11001553 in gene,rs56900803 in gene,rs7832767 in gene and rs11079571 in gene) were genotyped using MassARRAY method.

[Gene Mutation Spectrum Analysis of 170 Patients with Duchenne/Bayesian Muscular Dystrophy in Southwest of China].

Objective: To determine gene variations and genotype-phenotype correlations in Duchenne/Bayesian muscular mystrophy (DMD/BMD) patients, and the association between dystrophin gene polymorphisms and clinical phenotype.

Methods: Multiplex ligation-dependent probe amplification (MLPA) was adopted to detect dystrophin gene variations in 170 patients. Sanger sequencing was performed in 3 cases with decreased peaks in MLPA results.

[Microwave In-situ Regeneration of Cu-Mn-Ce/ZSM Catalyst Adsorbed Toluene and Distribution of Bed Temperature].

Microwave in-situ regeneration of Cu-Mn-Ce/ZSM catalyst adsorbed toluene, distribution of fixed bed temperature, adsorption breakthrough curves of the catalyst after several regenerations and characterizations of the catalyst by BET and SEM were investigated in this study. The research indicated that regeneration effect of the catalyst adsorbed was excellent under conditions of microwave power 117 W, air flow 0.5 m3 x h(-1) and catalyst dosage of 800 g.

[Catalytic oxidation of two-component VOCs and kinetic analysis ].

Catalytic oxidations of two-component volatile organic compounds (VOCs) toluene and chlorobenzene were investigated under microwave heating and tube furnace heating, respectively, and reaction kinetics were analyzed in this paper. The research indicated that competitive adsorption between toluene and chlorobenzene reduced their removal efficiencies by 3% -12% as compared to single component. 'Hot spot effect' and 'non-thermal effect' under microwave irradiation obviously enhanced conversion efficiencies of VOCs, especially, the chlorobenzene removal was increased by 31% -38%.