[Inhibitory effect of melatonin on morphine withdrawal syndromes and the content of NO in plasma and brain tissue in morphine dependent mice].

Aim: To observe the effect of melatonin (MT) on morphine withdrawal syndromes and determine the content of NO in plasma and brain tissue in morphine dependent mice.

Methods: A physical dependent model in mice was established by subcutaneous injection of morphine. MT (15 mg.