Needs for discharge planning and facilitators-barriers to implementing discharge plans for patients with SLE: A qualitative study.

Objective: To investigate the needs of patients with SLE in terms of discharge planning, to outline the practical perspectives of clinical healthcare professionals regarding the enablers and impediments to SLE patients' discharge planning, and to establish a basis for the creation of SLE discharge plans for subsequently diagnosed patients.

Methods: Descriptive qualitative research methodology was used in this study, with the researcher herself as the research instrument. Healthcare professionals formally employed in the rheumatology and immunology department, as well as SLE patients admitted to a tertiary-level hospital in Anhui Province between August and December 2023, were chosen for the study using a purposeful sample technique.

In vitro silencing of RIP2 in naive CD4 T cells from lupus-prone mice promotes pathogenic Th17 cell differentiation.

Objective: This work aims to investigate whether RIP2 silencing in naive CD4 T cells from lupus-prone mice impacts Th17 cell activity or differentiation in vitro.

Methods: Naive CD4 T cells isolation from MRL/lpr mice's spleens. Three RNA interference target sequences of RIP2 were packaged with lentivirus and transfected into naive CD4 T cells.

Current investigation of the high prevalence of sexual dysfunction in female patients with systemic lupus erythematosus: a cross-sectional study.

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects women of childbearing age and has been reported to cause sexual dysfunction in women. Although there are articles on sexual function in women with SLE, the number of articles is small, and the factors affecting sexual function in women with SLE are controversial. Based on this, this study aimed to investigate the prevalence of sexual dysfunction in Chinese female SLE patients and to explore the factors that influence it.

[Preparation and evaluation of a new xenogenic implant material].

Objective: To prepare a new xenogenic material using patented biochemical techniques for tissue disposal and investigate its possibility to be used as implant materials.

Methods: The xenogenic implant materials were prepared by treatment of fresh porcine tendon with epoxy cross-linking fixation, antigen minimization procedures, mechanical enhancement by protein molecule modification and surface treatments. Histological and scanning electron microscopic observations were conducted, and physicochemical property assessment was carried out to determine the mechanical properties, protein contents, polyepoxy compound residual and stability of the material.