[Expression and Biological Function of in Acute Myeloid Leukemia].

Objective: To study the expression of in patients with acute myeloid leukemia (AML) and its effect on proliferation, apoptosis and cycle of AML cells.

Methods: RT-qPCR was used to detect the expression of mRNA in bone marrow samples of patients with newly diagnosed AML and normal controls. The stable overexpression of in AML cell lines THP-1 and U937 were constructed by liposome transfection.