[Effects of nitrogen deposition on carbon and nitrogen contents in soil aggregates in temperate forests of Changbai Mountain, Northeast China.].

Nitrogen deposition is one of the most important factors affecting carbon (C) and nitrogen (N) cycling in terrestrial ecosystem. A six-year N addition experiment was carried out to explore how N deposition affected C and N fractions in soil aggregates in the secondary aspen forest (YHL) and primary Korean pine broad-leaved forest (HSL). We investigagted the effects of N addition on dissolved organic carbon and nitrogen (DOC and DON), microbial biomass carbon and nitrogen (MBC and MBN), particulate organic carbon and nitrogen (POC and PON) in soil aggregates with different particle sizes.

Cell Culture System for Analysis of Genetic Heterogeneity Within Hepatocellular Carcinomas and Response to Pharmacologic Agents.

Background & Aims: No targeted therapies have been found to be effective against hepatocellular carcinoma (HCC), possibly due to the large degree of intratumor heterogeneity. We performed genetic analyses of different regions of HCCs to evaluate levels of intratumor heterogeneity and associate alterations with responses to different pharmacologic agents.

Methods: We obtained samples of HCCs (associated with hepatitis B virus infection) from 10 patients undergoing curative resection, before adjuvant therapy, at hospitals in China.