A biomimetic orthogonal-bilayer tubular scaffold for the co-culture of endothelial cells and smooth muscle cells.

In blood vessels, endothelial cells (ECs) grow along the direction of blood flow, while smooth muscle cells (SMCs) grow circumferentially along the vessel wall. To mimic this structure, a polycaprolactone (PCL) tubular scaffold with orthogonally oriented bilayer nanofibers was prepared electrospinning and winding. ECs were cultured on the inner layer of the scaffold with axial nanofibers and SMCs were cultured on the outer layer of the scaffold with circumferential nanofibers.

EIT Imaging of Intracranial Hemorrhage in Rabbit Models Is Influenced by the Intactness of Cranium.

Electrical impedance tomography (EIT) has been shown to be a promising, bedside imaging method to monitor the progression of intracranial hemorrhage (ICH). However, the observed impedance changes within brain related to ICH differed among groups, and we hypothesized that the cranium intactness (open or closed) may be the one of potential reasons leading to the difference. Therefore, the aim of this study was to investigate this effect of open or closed cranium on impedance changes within brain in the rabbit ICH model.

Use of electrical impedance tomography to monitor regional cerebral edema during clinical dehydration treatment.

Objective: Variations of conductive fluid content in brain tissue (e.g. cerebral edema) change tissue impedance and can potentially be measured by Electrical Impedance Tomography (EIT), an emerging medical imaging technique.

MicroRNA-320 inhibits osteosarcoma cells proliferation by directly targeting fatty acid synthase.

Increasing evidence has demonstrated that small noncoding microRNAs (miRNAs) could contribute to cancer development and progression. Besides, they are differentially expressed in human tumor tissues. In the current study, we found that miR-320 was significantly downregulated in human osteosarcoma tissues, compared with adjacent normal tissues.

A new head phantom with realistic shape and spatially varying skull resistivity distribution.

Brain electrical impedance tomography (EIT) is an emerging method for monitoring brain injuries. To effectively evaluate brain EIT systems and reconstruction algorithms, we have developed a novel head phantom that features realistic anatomy and spatially varying skull resistivity. The head phantom was created with three layers, representing scalp, skull, and brain tissues.

A comparative proteomic study identified calreticulin and prohibitin up-regulated in adrenocortical carcinomas.

Background: Identifying novel tumor biomarkers to develop more effective diagnostic and therapeutic strategies for patients with ACC is urgently needed. The aim of the study was to compare the proteomic profiles between adrenocortical carcinomas (ACC) and normal adrenocortical tissues in order to identify novel potential biomarkers for ACC.

Methods: The protein samples from 12 ACC tissues and their paired adjacent normal adrenocortical tissues were profiled with two-dimensional electrophoresis; and differentially expressed proteins were identified by mass spectrometry.

[The study of the relationship between microlymphatic vessel density and lymph metastasis in hepatocellular carcinoma].

Not Abstract.

Self-organization of hydroxyapatite nanorods through oriented attachment.

The oriented attachment of hydroxyapatite (HAP) nanorods was achieved through a hydrothermal treatment. The nanorods were arranged in order along the c-axis of the HAP. These formed ca.

[A simulation study of electrical impedance scan-imaging based on a phantom].

Objective: To testify the feasibility of electrical impedance scanning (EIS) imaging and to classify the factors influencing EIS imaging at the early stage of electrical impedance scanning breast imaging study.

Method: Based on the EIS experiment workplace, a phantom to simulate the distribution of breast tissue was designed. Using NaCl solution and agar block with different conductance, three kinds of electric fields disturbances were simulated.

Induced current electrical impedance tomography system: experimental results and numerical simulations.

In electrical impedance tomography (EIT), measurements of developed surface potentials due to applied currents are used for the reconstruction of the conductivity distribution. Practical implementation of EIT systems is known to be problematic due to the high sensitivity to noise of such systems, leading to a poor imaging quality. In the present study, the performance of an induced current EIT (ICEIT) system, where eddy current is applied using magnetic induction, was studied by comparing the voltage measurements to simulated data, and examining the imaging quality with respect to simulated reconstructions for several phantom configurations.