Comparison of T lymphocyte subsets in aplastic anemia and hypoplastic myelodysplastic syndromes.

Aims: This study aims to compare the proportion of peripheral blood T lymphocyte subsets and related blood cell and bone marrow cytology indexes between patients with aplastic anemia (AA) and hypoplastic myelodysplastic syndrome (hypo-MDS), and investigate the clinical identification significance.

Materials And Methods: A total of 41 patients with AA and 46 patients with hypo-MDS were collected, and the proportions of peripheral blood T lymphocyte subsets, CD3CD16/CD56NK cells, CD3CD57T-LGL cells and CD19B lymphocytes were detected by flow cytometry.

Key Findings: The CD4/CD8 ratio decreased in the AA and hypo-MDS groups, and the difference was statistically significant when compared with that in the control group (P<0.