Publications by authors named "Xue-Ni Xu"
Article Synopsis
- The study investigates the role of microRNA-142-3p (miR-142-3p) in breast cancer, revealing that its expression is significantly lower in tumor tissues and cell lines compared to normal levels.* -
- Elevating miR-142-3p expression was found to inhibit both the growth and spread of breast cancer cells, as demonstrated through experiments both in vitro (in the lab) and in vivo (in live models).* -
- The mechanism involves the regulation of RAC1 protein levels by miR-142-3p, which subsequently affects proteins related to cancer progression, suggesting that targeting the miR-142-3p/RAC1/PAK1 pathway could offer new treatment
Colorectal cancer(CRC) is a prevalent malignancy in the world. There is growing evidence that microRNAs (miRNAs) as crucial modulator are in connection with many tumor-related diseases including CRC. Though miR-485-5p has been reported as an anti-oncogene in certain cancers, it remains unclear in CRC.
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