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Publications by authors named "Xue-Nan Zhang"

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Synopsis of recent research by authors named "Xue-Nan Zhang"

  • - Xue-Nan Zhang's recent research investigates the interaction between G-quadruplexes in chromosomal DNA and topoisomerase 1 activity, highlighting the negative regulation of this essential enzyme.
  • - The study, published in Nucleic Acids Research, elucidates the role of topoisomerase 1 in managing torsional stress during crucial cellular processes like transcription and replication.
  • - Findings suggest that the retention of non-working topoisomerase 1 on chromosomal DNA may be linked to the presence of G-quadruplexes, contributing to a better understanding of genome stability mechanisms.

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