Publications by authors named "Xue-Meng Yin"

Article Synopsis
  • Two halophilic archaea strains, TS33 and KZCA124, were isolated from distinct salt lakes in the Qinghai-Xizang Plateau and are identified as low abundant original inhabitants of those environments.
  • Both strains can grow under extreme conditions, thriving at temperatures between 20-60 °C and varying salinity (0.9-4.8 M NaCl), with respective optimal growth conditions indicated.
  • Genetic analyses suggest that TS33 and KZCA124 are closely related yet distinct enough to potentially classify them as a new species in a new genus within the Natrialbaceae family, as indicated by their unique lipid composition and phenotypic traits.
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  • Two halophilic archaeal strains, Gai3-2 and NJ-3-1, were discovered from samples gathered in China, showing high genetic similarity but distinct phylogenetic branches.
  • Their average nucleotide identity (ANI) and DNA-DNA hybridization (DDH) values were significantly lower than the species boundary thresholds, indicating they are likely separate species.
  • Consequently, Gai3-2 and NJ-3-1 have been classified as two new species within their genus, proposed to be named as sp. nov. and sp. nov. respectively.
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  • A study analyzed two unique halophilic archaeal strains, TH32 and YPL4, from salty environments in China, uncovering differences in their genetic makeup.
  • Both strains showed significant genetic similarities but had distinct phylogenetic branches and phenotypic characteristics, indicating they are separate species.
  • The research proposed these strains as new species based on lower average nucleotide identity (ANI) and DNA-DNA hybridization (DDH) values compared to existing members in the same group.
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  • Extracellular protease HlyA from Halococcus salifodinae was characterized for its robustness and optimal activity at 45°C, pH 9.0, and high NaCl concentrations.
  • HlyA demonstrates remarkable salinity tolerance, maintaining over 75% activity in a broad NaCl range, and is activated by metal ions like Ca, Mg, and Sr, while being inhibited by PMSF, indicating it is a serine protease.
  • The enzyme effectively degrades various protein substrates, showing potential for industrial applications due to its stability and performance under extreme conditions.
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Two halophilic archaeal strains, C90 and YPL13, were isolated from a salt lake and a salt mine in PR China. The two strains were found to form two clusters (97.5 and 89.

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Purpose: To observe the effect of gene therapy mediated by oral administration of attenuated Salmonella carrying tip30 and IFN-γ genes in human tongue carcinoma nude mouse model.

Methods: 25 four-week-old BALB/C male nude mice were divided randomly into 5 groups based on the differently harboring genes in the recombinant attenuated Salmonella typhimuriums SL7207, which included blank group (PBS), control group (SL7207), IFN treatments group (SL7207-pCI-IFN), tip30 treatment group (SL7207-pCI-tip30) and the combination of IFN and tip30 treatment group (SL7207-pCI-tip30/IFN). On 10d after submandibular subcutaneous injection of Tca8113 cells into the mice, the recombinant attenuated Salmonella typhimuriums were orally administrated 3 times at 1 week interval.

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Article Synopsis
  • The study aimed to assess the biocompatibility of a new diatomite-based ceramic by examining its effects on L929 cells in comparison to other prosthodontic materials.
  • Various concentrations of the ceramic and other materials were tested on a cell line, with apoptosis and cell cycle progression analyzed using flow cytometry and specific staining methods.
  • Results indicated that the new ceramic had no significant effect on cell apoptosis and demonstrated low cytotoxicity, aligning with the requirements for clinical biocompatibility.
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