Publications by authors named "Xue-Mei Shen"

The magnitude of the impact of altitude gradient on microbial community and diversity has been studied in recent decades. Whereas bacteria have been the focus of most studies, fungi have been given relatively less attention. As a vital part of the macro- and microscopic ecosystem, rhizosphere fungi play a key role in organic matter decomposition and relative abundance of plant species and have an impact on plant growth and development.

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Article Synopsis
  • Copy number variations (CNVs) are significant structural changes in the genome that have been increasingly identified in both humans and animals, but studies on their effects are still limited.
  • The study focused on the Apolipoprotein L3 gene, which is linked to important traits like meat quality, and examined CNV variations in 421 individuals from five cattle breeds.
  • Results showed a strong association between specific CNV polymorphisms and important growth traits, suggesting potential implications for improving cattle breeding practices.
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Objective: Lactobacilli in rabbit intestine is rare and its function on rabbit gut health is not fully understood. The present study aimed to evaluate in vivo the probiotic potential of Lactobacillus casei for suckling rabbits.

Methods: Two healthy 5-day-old suckling rabbits with similar weights from each of 12 New Zealand White litters were selected and disturbed to control group and treatment group.

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Brain-derived neurotrophic factor (BDNF) is a major neurotrophin in the central nervous system that plays a critical role in the physiological brain functions via its two independent receptors: tropomyosin-related kinase B (TrkB) and p75, especially in the neurodevelopment. Disrupting of BDNF and its downstream signals has been found in many neuropsychological diseases, including attention-deficit hyperactivity disorder (ADHD), a common mental disorder which is prevalent in childhood. Understanding the physiological functions of BDNF during neural development and its potential relationship with ADHD will help us to elucidate the possible mechanisms of ADHD and to develop therapeutic approaches for this disease.

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Objective: To prepare the self-microemulsifying soft capsule (SMESC) of Duyiwei and investigate its dissolution property.

Methods: Through solubility experiment, self-microemulsification in vitro, drawing phase diagram and investigating the stability of solution, the optimum formulation was determined for Duyiwei. The dissolution of SMESC was measured, taking the commercial capsule as reference.

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Objective: To study the optimum conditions for the isolation and purification of water-soluble substance from Salvia miltiorrhiza Bge.

Methods: The optimum macroporous resin was selected and the separation and purification process was evaluated by measuring the content of Salvianolic acid B in the fractions by HPLC.

Results: The XDA-5 macroporous resin was the most effective compared with other macroporous resins.

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