Efficacy-cost analysis of endoscopic mucosal resection and cold snare polypectomy: A propensity score matching analysis.

Background: Although substantial evidence supports the advantages of cold snare polypectomy (CSP) in terms of polypectomy efficacy and reduced postoperative adverse events, few studies have examined the cost differences between CSP and traditional endoscopic mucosal resection (EMR) for the treatment of intestinal polyps.

Aim: To compare the efficacy-cost of EMR and CSP in the treatment of intestinal polyps.

Methods: A total of 100 patients with intestinal polyps were included in the retrospective data of our hospital from April 2022 to May 2023.

Intestinal Microbiota Is Altered in Patients with Gastric Cancer from Shanxi Province, China.

Background: Many diseases have been associated with intestinal microbial dysbiosis. Host-microbial interactions regulate immune function, which influences the development of gastric cancer.

Aims: The aims were to investigate the characteristics of intestinal microbiota composition in gastric cancer patients and correlations between the intestinal microbiota and cellular immunity.

TIGAR knockdown enhanced the anticancer effect of aescin via regulating autophagy and apoptosis in colorectal cancer cells.

Our previous study showed that TP53-induced glycolysis and apoptosis regulator (TIGAR) regulated ROS, autophagy, and apoptosis in response to hypoxia and chemotherapeutic drugs. Aescin, a triterpene saponin, exerts anticancer effects and increases ROS levels. The ROS is a key upstream signaling to activate autophagy.