Publications by authors named "Xue-Man Zhang"
Article Synopsis
- The text discusses a new method for an organocatalytic asymmetric [3 + 2] cycloaddition involving β-trifluoromethyl enones and benzothiophene ketimines.
- This reaction produces a variety of spiro pyrrolidine-benzothiophenones with impressive stereocontrol, achieving a ratio of over 20:1 and up to 99% enantiomeric excess.
- The key takeaway is the highly efficient creation of unique spirocyclic compounds, which include a bis(trifluoromethyl)-substituted pyrrolidine structure with four consecutive stereocenters.
