Synergistic Al-Al Dual-Atomic Site for Efficient Artificial Nitrogen Fixation.

Synthesis of ammonia by electrochemical nitrogen reduction reaction (NRR) is a promising alternative to the Haber-Bosch process. However, it is commonly obstructed by the high activation energy. Here, we report the design and synthesis of an Al-Al bonded dual atomic catalyst stabilized within an amorphous nitrogen-doped porous carbon matrix (AlNC) with high NRR performance.

One-pot solvothermal synthesis of reduced graphene oxide-supported uniform PtCo nanocrystals for efficient and robust electrocatalysis.

Pt-based nanocomposites with low Pt utilization and high-activity by incorporating with other transition metals have received significant interest in catalysis. Meanwhile, loading Pt-based catalysts on graphene has great research value for improved stability and dispersity of the catalysts. Herein, a facile l-proline-mediated solvothermal strategy was reported to construct reduced graphene oxide (rGO) supported sheet-like PtCo nanocrystals (PtCo NCs/rGO) in ethylene glycol (EG).

HIF-1α protects against oxidative stress by directly targeting mitochondria.

The transcription factor hypoxia inducible factor-1α (HIF-1α) mediates adaptive responses to oxidative stress by nuclear translocation and regulation of gene expression. Mitochondrial changes are critical for the adaptive response to oxidative stress. However, the transcriptional and non-transcriptional mechanisms by which HIF-1α regulates mitochondria in response to oxidative stress are poorly understood.

Uric acid supported one-pot solvothermal fabrication of rhombic-like PtCu hollow nanocages for highly efficient and stable electrocatalysis.

High activity and good durability of electrocatalysts are of significance in practical applications of fuel cells. Among them, multi-component metallic hollow nanocages/nanoframes show great potential as advanced catalysts because of their highly open structures, large surface area and good stability. Herein, we report a general uric acid-mediated solvothermal method for shape-controlled synthesis of rhombic-like PtCu hollow nanocages (HNCs) with uric acid as co-reductant and co-structure-directing agent.

Facile solvothermal synthesis of PtCo lamellar nanoflowers as an efficient catalyst for oxygen reduction and methanol oxidation reactions.

The research for highly efficient and stable electrocatalysts in fuel cells has attracted substantial interest. Herein, bimetallic alloyed PtCo lamellar nanoflowers (LNFs) with abundant active sites were obtained by a one-pot solvothermal method, where cetyltrimethylammonium chloride (CTAC) and 1-nitroso-2-naphthol (1-N-2-N) served as co-structure-directors, while oleylamine (OAm) as the solvent and reducing agent. The fabricated PtCo LNFs exhibited the higher mass activity (MA, 128.

Facile solvothermal fabrication of polypyrrole sheets supported dendritic platinum-cobalt nanoclusters for highly efficient oxygen reduction and ethylene glycol oxidation.

Herein, uniform dendritic PtCo nanoclusters supported on sheet-like polypyrrole (PtCo NCs/PPy) were prepared by a facile one-pot solvothermal method. Cetyltrimethylammonium chloride (CTAC) and pyrrole worked as the capping agent and reductant, respectively, and pyrrole was in-situ polymerized to form PPy sheets under solvothermal conditions. The dendritic PtCo NCs/PPy had the enlarged electrochemically active surface area (EASA, 30.

Facile solvothermal fabrication of PtNi nanopolyhedrons for greatly boosting electrocatalytic performances for oxygen reduction and hydrogen evolution.

Pt-based bimetallic nanostructures with low content of Pt were considered as one of the attractive nanocatalysts for their high Pt utilization efficiency, remarkable catalytic characters and cost-effectiveness in facilitating the sluggish cathodic reactions in fuel cells. Herein, three-dimensional PtNi nanopolyhedrons (NPHs) with abundant active sites were constructed by a facile one-pot solvothermal strategy, in which cytosine and cetyltrimethylammonium chloride (CTAC) worked as the co-structure directing agents. The PtNi NPHs were mainly characterized by a series of techniques, showing the high catalytic activity and stability towards oxygen reduction reaction (ORR) and hydrogen evolution reaction (HER) in comparison to PtNi nanocrystals (NCs), PtNi NCs, commercial Pt black and/or Pt/C catalysts.

One-pot fabrication of reduced graphene oxide supported dendritic core-shell gold@gold-palladium nanoflowers for glycerol oxidation.

Herein, a one-pot wet-chemical route was used to prepare well-defined dendritic core-shell gold@gold-palladium nanoflowers supported on reduced graphene oxide (Au@AuPd NFs/rGO), using 2, 4-dihydroxypyridine (2, 4-DHP) asa new stabilizer and structure-director. Their morphology, size, composition, and crystal structure were characterized by a set of characterization techniques. Control experiments demonstrated that the molar ratio of the metal precursors and the dosage of 2,4-DHP play essential roles in this synthesis.

Regulatory network of microRNAs, target genes, transcription factors and host genes in endometrial cancer.

Genes and microRNAs (miRNAs) have important roles in human oncology. However, most of the biological factors are reported in disperse form which makes it hard to discover the pathology. In this study, genes and miRNAs involved in human endometrial cancer(EC) were collected and formed into regulatory networks following their interactive relations, including miRNAs targeting genes, transcription factors (TFs) regulating miRNAs and miRNAs included in their host genes.