Seven undescribed compounds from dried flower buds of Ochrocarpus longifolius.

Seven unreported compounds were isolated from dried flower buds of Ochrocarpus longifolius in this study, including an alkaloid ochrocaracid A (1), five coumarins ochrocarpins I (2), J (3), K (4), L (5), and M (6), and one styryl-2-pyranone compound iresinoacid (7) and nine known compounds (8-16). All these compounds were found in O. longifolius for the first time.

A new coumarin and a new flavonoid from .

A new coumarin () and a new flavonoid () were isolated from the air-dried flower buds of , together with ten known compounds (-). The structures of two new compounds were established by 1D and 2D NMR and MS data. In addition, the new compound showed significant proliferation inhibitory activity on Eca-109 and MGC-803 cells.

Nutritional Assessment Tools for Patients with Cancer: A Narrative Review.

Cancer patients are at high risk of malnutrition, which can lead to adverse health outcomes such as prolonged hospitalization, increased complications, and increased mortality. Accurate and timely nutritional assessment plays a critical role in effectively managing malnutrition in these patients. However, while many tools exist to assess malnutrition, there is no universally accepted standard.

Efficient modulation of cellular phosphorus components in response to phosphorus deficiency in the dinoflagellate .

Dinoflagellates are the most common phytoplankton group and account for more than 75% of harmful algal blooms in coastal waters. In recent decades, dinoflagellates seem to prevail in phosphate-depleted waters. However, the underlying acclimation mechanisms and competitive strategies of dinoflagellates in response to phosphorus deficiency are poorly understood, especially in terms of intracellular phosphorus modulation and recycling.

A study on the mechanism of the impact of phenthoate exposure on Prorocentrum lima.

Extensive application of organophosphorus pesticides such as phenthoate results in its abundance in ecosystems, particularly in waterbodies, thereby providing the impetus to assess its role in aquatic organisms. However, the impact of phenthoate on marine algal physiological and proteomic response is yet to be explored despite its biological significance. In this study, we thus ought to investigate the impact of phenthoate in the marine dinoflagellate Prorocentrum lima, which is known for synthesizing okadaic acid (OA), the toxin responsible for diarrhetic shellfish poisoning (DSP).

Transcriptome analysis reveals gene expression changes of the basidiomycetous yeast Apiotrichum mycotoxinivorans in response to ochratoxin A exposure.

Ochratoxin A (OTA) is one of the most common and deleterious mycotoxins found in food and feedstuffs worldwide; however, Apiotrichum mycotoxinivorans can detoxify OTA. Our results show that A. mycotoxinivorans GUM1709 efficiently degraded OTA, but it caused the accumulation of intracellular reactive oxygen species.

Functional Connectivity Differences in the Insular Sub-regions in Migraine without Aura: A Resting-State Functional Magnetic Resonance Imaging Study.

The objective of this study was to investigate resting-state functional connectivity (FC) differences in insular sub-regions during the interictal phase in patients with migraine without aura (MWoA). Forty-nine MWoA patients (MWoA group) and 48 healthy individuals (healthy control group) were recruited for this study. All of the subjects underwent neurological examination and magnetic resonance imaging (MRI).

[Ultrasonic monitoring foam sclerotherapy for serious varicosis of lower extremity].

Objective: To evaluate the efficacy and safety of foam sclerotherapy for lower extremity varicosis in C4 to C6 patients.

Methods: A total of 32 patients (32 limbs) with serious lower extremity varicosis classified as C4 to C6 were enrolled. Ultrasonic monitoring of foam sclerotherapy was performed after subfascial endoscopic perforator suture and saphenous vein ligation.

Differentially expressed microRNAs at different stages of atherosclerosis in ApoE-deficient mice.

Background: Atherosclerosis is the primary cause of cardiovascular disease, carotid artery disease, and peripheral vascular disease. However, it is hard to obtain human arterial tissue at different stages of atherosclerosis for a systematic study. The ApoE-deficient (ApoE(-/-)) mice predictably develop spontaneous atherosclerotic plaques with numerous features similar to the human lesions and contain nearly the entire spectrum of lesions observed during atherogenesis in humans.

[Ultrasound-guided compression repair for iatrogenic femoral artery pseudoaneurysm].

Objective: To evaluate relative factors affecting the efficiency of ultrasound-guided compression repair in iatrogenic femoral artery pseudoaneurysm.

Methods: Ultrasound-guided manual compression was performed in 42 patients of iatrogenic femoral artery pseudoaneurysm from June 2004 to June 2010. There were 28 male and 14 female patients, with a mean age of (52 ± 5) years.

MicroRNA-21 regulates vascular smooth muscle cell function via targeting tropomyosin 1 in arteriosclerosis obliterans of lower extremities.

Objective: The goal of this study was to determine the expression signature and the potential role of microRNAs in human arteries with arteriosclerosis obliterans (ASO).

Methods And Results: The expression profiles of microRNAs in human arteries with ASO and in normal control arteries were determined by quantitative reverse transcription-polymerase chain reaction array. Among the 617 detected microRNAs, multiple microRNAs were aberrantly expressed in arteries with ASO.

Tolerable hemodynamic changes after femoral artery ligation for the treatment of infected femoral artery pseudoaneurysm.

Background: We analyzed the hemodynamic changes induced by femoral artery ligation with concomitant thrombectomy in intravenous drug abusers with infected femoral artery pseudoaneurysm (IFAP) and their clinical significance.

Methods: Between January 2000 and November 2007, a total of 55 patients presented to our clinic with IFAP. Among these patients, 54 were treated by femoral artery ligation with concomitant thrombectomy.

Stent-grafting for unfavorable abdominal aortic aneurysm: a practical challenge.

Background: The endovascular treatment of abdominal aortic aneurysm (AAA) has improved greatly in the last 15 years. The present study aimed to evaluate the endografting experience for the treatment of unfavorable abdominal aortic aneurysm (uAAA).

Methods: During December 2001 and December 2007, 41 patients with uAAA were treated with endografting using concomitant techniques.

[A random, comparative study on endovenous laser therapy and saphenous veins stripping for the treatment of great saphenous vein incompetence].

Objective: To evaluate the therapeutic effects of endovenous laser therapy (EVLT) and saphenous veins stripping in the treatment of great saphenous vein incompetence.

Methods: Eighty cases (80 limbs) with great incompetent saphenous vein were randomly divided into 2 equal groups: EVLT group and stripping group. The patients in the EVLT group underwent EVLT and those in the stripping group underwent upper ligation and stripping of great saphenous vein.

[Study on culture, identification and differentiation of CD133+ endothelial progenitor cells from human umbilical cord blood].

Objective: To study the isolation, culture and identification of CD133+ endothelial progenitor cells (EPCs) from human umbilical cord blood in vitro.

Methods: EPC separation was performed with density gradient centrifugation and MACS separation. Purity of EPCs was determined by flow cytometry.

[Selection of the initial surgery extent for differentiated thyroid cancer without metastasis].

Objective: To discuss the selection of the initial surgery extent for differentiated thyroid cancer (DTC) without metastasis.

Methods: The clinical data of 504 cases with DTC, who accepted the surgical treatment from Jan 1995 to Dec 2004, were analyzed and studied. There were 329 cases without metastasis.

Effect of external valvuloplasty of the deep vein in the treatment of chronic venous insufficiency of the lower extremity.

Objective: This study was conducted to verify the efficacy of external valvuloplasty of the femoral vein in the treatment of primary chronic venous insufficiency (PCVI).

Methods: Forty patients with PCVI of the bilateral lower extremities were enrolled at the time of surgical management. All 80 limbs were classified as CEAP C2 to C4, with moderate incompetence of the deep vein.

[Static pressure induces vascular smooth muscle cells proliferation and apoptosis].

Objective: To study the role of static pressure on proliferation and apoptosis of the vascular smooth muscle cells.

Methods: Vascular smooth muscle cell line A10 were cultured at normal atmosphere, 80 mmHg, 100 mmHg, 200 mmHg static pressure respectively. Cell viability was determined by MTT assay, cell cycle and apoptosis rate were analyzed by flow cytometer.

[Effect of external vavuloplasty of deep vein in the treatment of chronic venous insufficiency of lower extremity].

Objective: To verify the role and effect of external vavuloplasty in the treatment of chronic venous insufficiency (CVI) of lower extremity.

Methods: Thirty patients with CVI of bilateral lower extremities were enrolled to accept surgical management of vein systems. Both limbs of each patient were randomized into two groups respectively according to the operating style.

[Surgical treatment for patients with primary hyperparathyroidism].

Objective: To evaluate the feasibility and efficacy of surgical treatment for patients with primary hyperparathyroidism (pHPT).

Methods: The studies were analyzed for 55 patients with pHPT who underwent parathyroidectomy in our hospital from 1985 to 2002.

Results: Eight patients were asymptomatic.

Cryopreservation of mango (Mangifera indica L.) embryogenic cultures.

Three techniques were compared for cryopreserving embryogenic masses (EMs) sampled from mango (Mangifera indica L.) cv. Zihua embryogenic cultures: (i) encapsulation/dehydration; (ii) pregrowth/dehydration; and (iii) vitrification.

[Default of KIAA0353 gene in varicose great saphenous vein accompanying primary deep vein valve insufficiency].

Objective: To screen and identify the genes related to the occurrence and development of varicose great saphenous vein in the patients with primary deep vein valve insufficiency (PDVI).

Methods: mRNA fluorescent differential display (FDD) technique was used to compare the different cDNA fragments originated from differentially expressed mRNAs from the venous tissues of 10 patients with varicose great saphenous vein complicated with PDVI. Ten specimens of normal venous tissue from 10 patients dying from other diseases were used as controls.

Quantitative assessment of the degree of deep venous reflux of the lower extremities.

Objective: We sought to quantitatively evaluate the degree of deep venous reflux of the lower extremities using colour Doppler velocity profile (CDVP) technology.

Methods: Deep venous reflux volume was examined using CDVP in 79 limbs of 66 patients who were admitted to our hospital between July 1999 and July 2000 with primary, deep venous, valvular incompetence. Reflux data were statistically described and analyzed.