Publications by authors named "Xue-Li Gao"
Moderate non-covalent interaction of protein and polyphenols can improve the emulsifying property of protein itself. The corn protein hydrolysate (CPH) and tannic acid (TA) complex was successfully used to construct nanoemulsion for algal oil delivery. There has been no study on the feasibility of this nanoemulsion delivery system for other food functional components, for example, β-carotene (β-CE).
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- Iron is crucial for life, but too much can harm organs; this study examines how iron overload affects liver injury in chicks by influencing specific signaling pathways.
- Researchers fed 150 one-day-old broiler chicks different amounts of ferrous sulfate and analyzed the effects after 14 days, finding signs of liver damage and increased expression of stress-related proteins.
- The findings suggest a link between endoplasmic reticulum stress and the PI3K/AKT/mTOR pathway in causing liver injury, indicating that excessive iron can lead to cell death in the liver.
Article Synopsis
- Birds infected with Reticuloendotheliosis virus (REV) experience immunosuppression, affecting their immune organs like the thymus, bursa of Fabricius, and spleen.
- The study investigates how the TLR-3/IFN-β pathway is disrupted in chickens by analyzing changes in immune response at various time points after infection.
- Results indicate that TLR-3, IRF-7, and NF-κB p65 levels change significantly during early REV infection, with a later decrease in NF-κB p65 correlating with reduced IFN-β levels, highlighting a complex interaction in the immune response.
Background: Reticuloendotheliosis virus (REV) is a retrovirus that causes severe immunosuppression in poultry. Animals grow slowly under conditions of oxidative stress. In addition, long-term oxidative stress can impair immune function, as well as accelerate aging and death.
View Article and Find Full Text PDFThe aim of this work is to investigate the relationship between iron and oxidative stress in the immune organs of excessive iron-fed sheep. Sixteen German Mutton Merino rams were randomly divided into 4 groups, which were fed the basal diets supplemented with 50 (CON), 500 (L-iron), 1000 (M-iron), and 1500 (H-iron) mg Fe/kg as ferrous sulfate monohydrate (FeSO·HO), respectively. The actual iron content in the diet was determined to be 457.
View Article and Find Full Text PDFReticuloendotheliosis virus (REV), an avian retrovirus is able to infect a variety of birds and can cause immunosuppression. The aim of this study was to investigate the relationship of thymic lymphocytes apoptosis, proliferation and T cell subtype with immunosuppression. In this study, a hundred and twenty one-day old SPF chickens were randomly divided into control groups (group C) and a REV infection groups (group I).
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