Publications by authors named "Xue-Lei Gong"
Article Synopsis
- Group B Streptococcus (GBS) is a major cause of severe infections in newborns, and its impact on gut microbiota during early life could increase disease risk later on.
- Analysis of meconium microbiota showed that while overall composition was similar in infants with and without GBS, there were significant differences in specific bacterial taxa, notably a decrease in Lactobacillus paracasei in the GBS group.
- This study highlights the potential link between maternal GBS colonization and initial gut microbiota imbalances in neonates, suggesting that such dysbiosis may be important for understanding GBS colonization.
Beneficial Effects of Probiotic Treatment on Gut Microbiota in Very Low Birth Weight Infants.
Gastroenterol Res Pract
October 2019
The very low birth weight (VLBW) infant is at great risk for marked dysbiosis of the gut microbiota. In the present study, a total of 36 VLBW infants were randomly divided into two groups, who were treated with combined probiotics and placebo, and 72 fecal specimens on days 14 and 28 of life were collected from them. Finally, 32 fecal specimens extracted from 16 preterm VLBW infants were qualified and analyzed using 16S rRNA gene sequencing.
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