Publications by authors named "Xue-Juan Lu"
Article Synopsis
- Asprosin, a protein hormone linked to metabolic diseases, was found to affect the proliferation and migration of vascular smooth muscle cells (VSMCs) in a rat model of hypertension, indicating its potential role in cardiovascular diseases.
- The study showed that asprosin levels were higher in the VSMCs of hypertensive rats, and it promoted their proliferation and migration by increasing the activity of Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase and superoxide production.
- Knocking down asprosin reduced VSMC proliferation and migration, suggesting that targeting asprosin could help alleviate vascular remodeling and high blood pressure in hypertensive conditions.
