Homeostatic and early-recruited CD101 eosinophils suppress endotoxin-induced acute lung injury.

Introduction: Acute lung injury (ALI) is a fatal but undertreated condition with severe neutrophilic inflammation, although little is known about the functions of eosinophils in the pathogenesis of ALI. Our objectives were to investigate the roles and molecular mechanisms of eosinophils in ALI.

Methods: Pulmonary eosinophils were identified by flow cytometry.