Publications by authors named "Xue-Dong Lv"

Objective: This study investigated the expression and clinical significance of Melanoma Associated Antigen (MAGE)-A proteins and mRNA in patients with non-small cell lung cancer (NSCLC).

Methods: A retrospective study was conducted, and we selected a cohort of 88 NSCLC patients treated at our hospital from January 2015 to January 2020. Adjacent tissues were chosen as controls.

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Article Synopsis
  • Self-expandable metallic (SEM) airway stents are used to treat malignant central airway obstructions and this study compares the operation time and safety between the traditional over-the-wire (OTW) stent and a new through-the-scope (TTS) SEM stent.
  • A total of 148 patients were enrolled, with 134 analyzed, showing that the TTS group had a significantly shorter operation time compared to the OTW group (104 seconds vs. 252 seconds).
  • Although the TTS group had higher efficacy rates and lower rates of complications like granulation and restenosis, these differences did not reach statistical significance.
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Background: Lung cancer is the leading cause of cancer-related deaths worldwide, with non-small cell lung cancer (NSCLC) accounting for 85% of all lung cancer cases. Inflammation has been proven to be one of the characteristics of malignant tumors. Chronic inflammatory response mediated by cytokines in the tumor microenvironment is an important factor in tumorigenesis.

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Non-small cell lung cancer (NSCLC) is one of the most common causes of tumor-associated mortality worldwide. Early diagnosis is the key focus for improving prognosis. In the present study, the association between exhaled breath condensate (EBC) let-7 and NSCLC diagnosis and clinicopathologic characteristics was investigated in order to explore non-invasive simple technological therapeutic methods.

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BACKGROUND Ultrasound elastography is an imaging modality used to show tissue stiffness in tumor pathophysiological processes that promote the formation of stiffer tissues. Endobronchial ultrasound (EBUS) elastography is an ultrasound elastography-based technique for measuring tissue stiffness during EBUS-guided transbronchial needle aspiration (EBUS-TBNA). The diagnostic value of EBUS elastography in central lung lesions remains largely unknown.

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The present study aimed to investigate the clinical significance of cancer embryo antigen (CEA) and endothelin-1 (ET-1) in the exhaled breath condensate (EBC) of patients with non-small cell lung cancer (NSCLC). EBC samples were collected from 143 patients with NSCLC and 119 healthy individuals by using an EBC collector. The CEA and ET-1 levels in the EBC and serum were detected.

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