Publications by authors named "Xue-Cheng Gao"

Objective: Clinical practice guidelines can improve healthcare processes and patient outcomes; however, the quality of these guidelines varies greatly in China. The aim of this study was to construct a comprehensive instrument for the appraisal of clinical practice guidelines in China (AGREE-CHINA), and to validate its reliability as a tool for helping potential guideline users in assessing guideline quality.

Methods: First, an interdisciplinary working group was established for developing the methods.

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The aim of this study was to investigate the transdermal penetration enhancement effect of wintergreen oil and its action mechanisms. The in vitro transdermal tests were carried out to study the transdermal penetration enhancement effect of wintergreen oil by using osthole and geniposide as the lipophilic and hydriphilic model drugs. Fourier-transform infrared spectroscopy was used to investigate the effect of wintergreen oil on the molecular structure of rat stratum corneum, and the scanning electron microscope was employed to observe the change of rat skin surface after treatment by the oil.

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Objective: To investigate the prevalence and causes of blindness and moderate and severe visual impairment among adults aged ≥ 50 years in Luxi County of Yunnan Province, China.

Methods: It was a population-based cross-section study. Geographically defined cluster sampling was used in randomly selecting 5575 individuals aged ≥ 50 years in Luxi County.

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Objective: To investigate the prevalence and causes of blindness and moderate and severe visual impairment among adults aged ≥ 50 years in Changji City of Xinjiang Uygur Autonomous Region, China.

Methods: It was a population-based cross-section study.Geographically defined cluster sampling was used in randomly selecting 5714 individuals aged ≥ 50 years in Changji City.

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Objective: To investigate the prevalence and causes of blindness and moderate and severe visual impairment among adults aged ≥ 50 years in Longyao County, Hebei Province, China.

Methods: It was a population-based cross-section study.Geographically defined cluster sampling was used in randomly selecting 5527 individuals aged ≥ 50 years in Longyao County.

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Objective: To investigate the prevalence and causes of blindness and moderate and severe visual impairment among adults aged 50 years or above in Yongchuan of Chongqing City, China.

Methods: It was a population-based cross-section study.Geographically defined cluster sampling was used in randomly selecting 5663 individuals aged ≥ 50 years in Yongchuan District.

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Article Synopsis
  • A study in Ji'an county, China, assessed cataract prevalence, surgical outcomes, and their social impact on individuals aged 50 and above, finding a cataract prevalence of 23.11%.
  • Among the 5010 individuals examined, cataract surgeries mostly involved modern techniques with a relatively low surgical coverage rate of 32.29% and a social burden of 3.83% due to cataract blindness.
  • Results indicated that older females are at higher risk, and many operated eyes did not achieve optimal visual acuity due to issues like post-capsular opacity and refractive errors.
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Article Synopsis
  • The study aimed to assess the rates of blindness and visual impairments in adults aged 50 and older in Ji'an County, China, using a population-based approach with a large sample size of over 5,000 participants.
  • Results showed a blindness prevalence of 1.56% and moderate to severe visual impairment at 5.29% when considering best corrected visual acuity, with rates rising among older adults, women, and those with lower education levels.
  • The findings highlight cataracts as the leading cause of visual impairment in this demographic, underscoring the need for targeted eye health interventions in the region.
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Objective: To estimate the prevalence of cataract, the rate of cataract surgical coverage rate,and the rate of cataract-blindness social burden among older adults aged 50 years or above in Qidong City of Jiangsu Province, China, in 2006.

Methods: Cluster sampling was used in randomly selected 5662 individuals aged 50 years or above in 16 clusters in Qidong City. 5141 individuals received visual acuity and eye examination from September to December 2006.

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Objective: To assess the prevalence of cataract, the outcomes of cataract surgery, the rate of cataract surgical coverage, and the rate of cataract blindness social burden.

Methods: Cluster sampling was used in 5118 randomly selected individuals aged > or = 50 years in the Shunyi district of Beijing from April to August 2006. All individuals were received visual acuity and eye examination, including the evaluation of lens status and cataract surgical status by slit lamp biomicroscopy.

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Objective: To estimate the prevalence of blindness and low vision among older adults aged > or = 50 years in Qidong City of Jiangsu Province, China, in 2006.

Methods: Cluster sampling was used in randomly selecting 5662 individuals aged > or = 50 years from September to December 2006 in 16 clusters in Qidong City. The survey was preceded by a pilot study where operational methods were refined and quality assurance evaluation was carried out.

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Unlabelled: OBJECTIVE To assess the prevalence of blindness and moderate and severe visual impairment among adults aged 50 years or above in the Shunyi district of Beijing,China.

Methods: It was a population-based cross-section study. Geographically defined cluster sampling was used in 5840 randomly selected individuals aged > or = 50 years in 28 clusters in the Shunyi district from April to August 2006.

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Article Synopsis
  • The objective of the study was to create a protocol for a nationwide survey assessing blindness, visual impairment, and cataract surgery in China, focusing on their prevalence and causes.
  • Methods for the protocol were based on previous studies and involved expert consultations, resulting in a comprehensive plan approved by health authorities and the WHO.
  • The finalized protocol established a standard approach for conducting the survey, detailing aspects like target populations, sample size calculations, and quality control measures.
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