Purpose: Carbohydrate intake has been linked to colorectal cancer (CRC) risk, with variations depending on the quantity and quality of carbohydrates consumed. This study aimed to investigate the association between carbohydrate quantity and quality, using the low-carbohydrate diet score (LCD) and carbohydrate quality index (CQI), and the risk of CRC in the Chinese population.
Methods: We conducted a case-control study in Guangzhou, China, with 2,799 CRC cases and an equal number of sex- and age-matched controls.
Background: Vitamin D might have anti-tumor effect, which is affected by the genes related to vitamin D metabolic pathway. Epigenetic mechanism may affect the expression level of vitamin D metabolic pathway related genes, then plays an important role in the occurrence and development of colorectal cancer. To date, no study has reported on the association between blood-based DNA methylation level of vitamin D metabolic pathway related genes and colorectal cancer risk.
View Article and Find Full Text PDFPurpose: We examined the association between whole grain and refined grain intake with all-cause, cancer and cardiovascular disease (CVD) mortality using the data from the Guangzhou Biobank Cohort Study.
Methods: 19,597 participants aged 50+ years were recruited from 2003 to 2006 and followed-up until April 2021. Multivariable Cox regression was used to calculate hazard radios (HRs) and 95% confidence intervals (CIs).
The long-term effects of a low-carbohydrate diet (LCD) on mortality, accounting for the quality and source of the carbohydrate, are unclear. Hence, we examined the associations of LCDs with all-cause and cause-specific mortality in a prospective cohort study. A total of 20,206 participants (13.
View Article and Find Full Text PDFObjective: To determine whether involvement in bullying as a bully, victim, or bully-victim was associated with a higher risk of poor sleep quality among high school students in China.
Methods: A cross-sectional study was conducted. A total of 23,877 high school students were surveyed in six cities in Guangdong Province.
Objectives: Previous studies indicated that cigarette smokers were more likely to develop hypertension, and both smoking and hypertension were associated with inflammation. Whether inflammation mediates the relationship of them is unclear. This study aims to examine whether inflammation mediates the association between smoking and hypertension.
View Article and Find Full Text PDFBackground: The deleterious biological effects of low-level, long-term exposure to heavy metals are well known, and children are the most susceptible population. Dabaoshan Mine in the southeast of Guangdong Province is at high risk of discharging multi-metals pollutants into a local river (Hengshihe) and the surrounding area. The present study aimed to estimate relationships between measured multi-metal exposures and the presence of behavioural problems for the school-aged children in the polluted area.
View Article and Find Full Text PDFBackground: Childhood obesity is a widespread and growing problem in the world. Body mass index (BMI) and weight-for-height criterion have been used to determine childhood obesity. No data was available to evaluate cardiovascular risk factors in overweight and obese Chinese children screened by weight-for-height index and Chinese newly developed BMI criterion.
View Article and Find Full Text PDFObjective: The objective of this study was to observe the variation of energy intake and energy expenditure in the obese Chinese children.
Methods: Basic metabolic rate was measured by using open-circuit indirect calorimetry in 54 obese children and 60 non-obese children aged 10-12 years in a full- time boarding school in Guangzhou suburb, China. Total energy expenditure was estimated by using a factorial method.
Zhonghua Liu Xing Bing Xue Za Zhi
November 2007
Objective: To explore the relationship between psychological stress, fatigue and different smoking behaviors among undergraduate students.
Methods: 8138 undergraduate students in grade 1 to 3 were sampled with cluster sampling method from a comprehensive university in Guangzhou, and were studied on their psychological stress, peer and self smoking behaviors, as well as socio-demographic factors with a self-administered questionnaire. Physical and mental fatigue was measured by Chalder fatigue scale.
Objective: To analyze the direct and indirect outcomes of influencing factors on smoking behaviors among adolescents.
Methods: Self-administered questionnaires were used to collect smoking-related information from 2021 respondents. Measurement models were built by confirmatory factor analysis and parameters were estimated by ERLS method.
Zhonghua Liu Xing Bing Xue Za Zhi
November 2005
Objective: To explore the influencing factors of smoking behavior transition at different stage of smoking among undergraduate students.
Methods: 8138 undergraduate students from grade 1 to 3 were selected using cluster sampling method from an university in Guangzhou with their smoking behaviors and relevant factors studied through a self-administered questionnaire. Beginners, un-regular smokers and regular smokers were defined as "case group", while non-smokers, beginners and un-regular smokers were defined as "control group" accordingly.