Publications by authors named "Xue P Chen"

Article Synopsis
  • Researchers explored the connection between Zinc finger (ZNF) proteins and Parkinson's disease (PD), focusing on a large cohort of Chinese patients with early-onset PD.
  • They identified rare genetic variants linked to PD in specific ZNF genes, particularly ZNF746 and ZNF219, with some variants showing significant associations to the disease.
  • This study enhances the understanding of the genetic relationship between ZNF proteins and PD, suggesting that ZNF746 may play a crucial role in early-onset forms of the disease.
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Methane production by methanogens in wetland is recognized as a significant contributor to global warming. Spartina alterniflora (S. alterniflora), which is an invasion plant in China's wetland, was reported to have enormous effects on methane production.

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Transcription factories have been characterized in cultured mammalian cells, but little is known about the regulation of these nuclear structures in different primary cell types. Using marine medaka, we observed transcription sites labeled by the metabolic incorporation of 5-fluorouridine (5-FU) into nascent RNA. Medaka was permeable to 5-FU in ambient water and became fully labeled within 4 hr of incubation.

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