Publications by authors named "Xue Nan Xuan"

Article Synopsis
  • The study sequenced and analyzed the whole genome of the Babesia gibsoni parasite, which causes babesiosis in dogs, revealing a total genome size of 7.94 Mbp and confirming its four chromosomes, apicoplast, and mitochondrion.* -
  • Bioinformatics analysis identified thousands of proteins and metabolic pathways, indicating a minimal genome size and revealing specific proteins that may play roles in the parasite's invasion and survival.* -
  • This research is significant as it fills gaps in the understanding of B. gibsoni's genetics and evolutionary history, potentially aiding in the development of better diagnostic tools, treatments, and vaccines.*
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Background: Neospora caninum is one of the main causes of abortion in pregnant animals. However, N. caninum-induced reproductive injury in male mice is still unclear.

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Ticks are the vectors of various pathogens, threatening human health and animal production across the globe. Here, for the first time we detected Ricketssia spp., Borrelia spp.

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Neospora caninum is the etiologic agent of bovine neosporosis, which affects the reproductive performance of cattle worldwide. The transmembrane protein, NcSRS2, and dense-granule protein, NcGRA7, were identified as protective antigens based on their ability to induce significant protective immune responses in murine neosporosis models. In the current study, NcSRS2 and NcGRA7 genes were spliced by overlap-extension PCR in a recombinant adenovirus termed Ad5-NcSRS2-NcGRA 7, expressing the NcSRS2-NcGRA7 gene, and the efficacy was evaluated in mice.

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