Development of a core outcome set and core measurement set for kangaroo mother care: a study protocol.

Background: Kangaroo mother care (KMC) is a care of preterm and low birthweight infants carried skin-to-skin contact with the mother's chest and breastfeeding when possible. KMC has been proven to reduce mortality and morbidity in these infants. However, research on KMC has been limited by significant variability and inconsistency in reported outcomes across studies.

[Changes of Peripheral Blood Marrow-Derived Suppressor Cell Level after Chemotherapy Induction Remission by VDLP Regimen and Their Relationship with Immune System in B-ALL Children].

Objective: To investigate the changes of peripheral blood marrow-derived suppressor cell level after chemotherapy induction remission by regimen consisting of vincristine, daunorubicin, L-asparaginase and prednisone (VDLP) and to analyze their relationship with immume system in B-ALL children.

Methods: Thirty B-ALL children after induction remission by VDLP regimen from August 2015 to August 2016 were selected as B-ALL group and 30 normal healthy children were selected as control group. The peripheral blood in 2 groups was collected and detected by flow cytometry, then the ratios of CD30 cells and CD33 HLA-DR marrow-derived suppressor cells, CD14CD33HLA-DR marrow-derived suppressor cells and CD15CD33HLA-DR marrow-derived suppressor cells were calculated, and their changes after induction remission by VDLP regimen and the relationship with immune system were analyzed.

Polychlorinated biphenyls and breast cancer: A congener-specific meta-analysis.

The incidence of breast cancer is related to various risk factors, especially that the environmental and lifestyle factors account for major contribution at the rate of 70% to 95% over all. However, there still remains some controversy over the epidemiological evidence regarding the effects of environmental carcinogens on the risk of breast cancer. We conducted a quantitative meta-analysis aiming at full evaluation of the effects of polychlorinated biphenyls (PCBs) on breast cancer in a congener-specific fashion.

[Small hepatocellular carcinoma in patients with hepatitis B-induced cirrhosis: a comparison between MRI and MDCT].

Objective: To compare efficacy of plain and contrast enhancement MRI (1.5T or 3T) and dynamic contrast enhanced multidetector CT (MDCT, 16- or 64 -slice) for the detection of small hepatocellular carcinoma (HCC) in patients with hepatitis B-induced cirrhosis.

Methods: A total of 21 patients (18 men, 3 women; age range, 44-74 years) with 22 small HCC and liver cirrhosis were enrolled, all having undergone MDCT and MRI within one month.

Using CT imaging to delineate the prostatic apex for radiation treatment planning.

Background And Objective: In computed tomography (CT)-based radiotherapy planning for prostate cancer, it is difficult to precisely delineate the prostatic apex because of its relationship with the urogenital diaphragm and bulbospongiosus musculature. In this retrospective study, we analyzed the magnetic resonance imaging (MRI) and CT scans of the patients with prostate cancer to investigate the relationship between the prostatic apex and the anatomic structure visible on CT, and to provide evidence for localizing the prostatic apex in radiotherapy planning.

Methods: MRI and CT scans of 108 patients with prostate cancer were analyzed to measure the distances between the prostatic apex and the bottom of ischial tuberosities, the bottom of obturator foramen, the bottom of pubic symphysis, and the bulb of the penis.

[Application of artificial neural network to diagnosis of prostate cancer].

Prostatic carcinoma is the fifth most common cancer in the world and the second most common in men. It is quite important to early detect and diagnose prostate cancer to reduce the mortality. With the increasing of the diagnosis and treatment tasks of prostate cancer and the development of medical techniques, more and more clinical and lab examinations, biopsy and medical imaging techniques are included in the diagnosis of prostate cancer.

[Molecular mechanisms of two novel mutations of factor XIII gene resulting in hereditary coagulation deficiency].

Objective: To investigate the mechanisms of two novel missense mutations of factor XIIIA subunit gene (Arg77-->Cys,Ser413-->Trp) in the pathogenesis of hereditary factor XIII deficiency.

Methods: Site-directed mutagenesis was conducted to obtain 2 mutant human XIII A recombinant plasmids, mut-PCI/FXIIIA. Normal wild type factor XIII A recombinant plasmid, wt-PCI/FXIIIA, and mut-PCI/FXIIIA, were transfected into cultured COS7 cells line, renal fibroid cell of African green monkey using Superfect reagent respectively, The expression levels of DNA, RNA and protein of human factor XIII, both wild type and mutant, were detected by PCR, RT-PCR and Western blotting.