Prior research has highlighted the reduction of iron oxide nanoparticle (IONPs) sizes to the "ultra-small" dimension as a pivotal approach in developing T-MRI contrast agents, and the enhancement in T contrast performance with the reducing size is usually attributed to the increased specific surface area and weakened magnetization. Nonetheless, as the size decreases, the variation in surface defects, particularly oxygen vacancy (V) defects, significantly impacts the T imaging efficacy. In this study, the V on IONPs is meticulously investigated through XPS, Raman, and EPR spectroscopy.
View Article and Find Full Text PDFInt J Hyperthermia
November 2023
Aim: The use of magnetic carbon nanotubes for multi-modal cancer treatment, incorporating both hyperthermia and drug delivery functions, has drawn substantial interest. Yet, the present method of regulating hyperthermia temperature involves manually adjusting the magnetic field intensity, adding to the complexity and difficulty of clinical applications. This study seeks to design novel magnetic carbon nanotubes capable of self-temperature regulation, and investigate their drug loading and release characteristics.
View Article and Find Full Text PDFRecently, embryo muscle development, which is crucial for postnatal skeletal muscle growth, has been investigated widely. Nutrients in ovo were suggested to be critical in embryo muscle development since the chick growth mostly relies on nutrients in eggs at the early developmental stage. Phytosterol esters (PE), which are derived from the reactions between phytosterols and fatty acids, were demonstrated to have important effects on lipid and cholesterol metabolism regulation.
View Article and Find Full Text PDFMagnetic hyperthermia can enhance the anti-tumor effects of chemotherapy. As carbon nanotubes are ideal drug carriers for chemotherapy, their combination with magnetic nanoparticles provides a novel chance for multi-modal thermo-chemotherapy. Most related work focuses on attaching FeO nanoparticles on carbon nanotubes, however the hyperthermia temperature for this combination can not be self-regulated due to the high Curie temperature of FeO.
View Article and Find Full Text PDFFor hyperthermia to be used under clinical conditions for cancer therapeutics the temperature regulation needs to be precise and accurately controllable. In the case of the metal nanoparticles used for such activities, a high coercivity is a prerequisite in order to couple more energy in a single heating cycle for efficient and faster differential heating. The chemically stable Co-Zn ferrite nanoparticles have typically not been used in such self-regulating hyperthermia temperature applications to date due to their low Curie temperature usually accompanied by a poor coercivity.
View Article and Find Full Text PDFThe low coercivity of spinel ferrites is a major barrier that significantly limits their use in high density magnetic recording applications. By controlling the substituting content of Cr(3+), in this article we describe how magnetic CoCr x Fe2-x O4 (0 < x < 1.2) nanoparticles with coercivity of up to 6.
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