Cutting Skill Assessment by Motion Analysis Using Deep Learning and Spatial Marker Tracking.

The assessment of surgical skill is crucial for indicating a surgeon's proficiency. While motion analysis of surgical tools is widely used in endoscopic surgery, it is not commonly applied to open surgery. Instead, open surgery skill assessment relies on observing the trajectory of surgical tools on tissue.

Quaternized cross-linked peach gum polysaccharide as an adsorbent for fast and selective removal of anionic dyes from aqueous solution.

To overcome low adsorption capacity, slow adsorption rate, poor adsorption selectivity, and dissolution of peach gum polysaccharide (PGP), an amino-rich crosslinked PGP (ACPGP) was first synthesized by cross-linking highly soluble PGP. Subsequently, a cation-rich PGP (QCPGP) was prepared from ACPGP through the addition of glycidyltrimethyl ammonium chloride (GTAC) and a secondary quaternization. The step-by-step preparation process was confirmed, and the adsorption properties of PGP, ACPGP, and QCPGP were compared in detail.

A Modified Preassigned Finite-Time Control Scheme for Spacecraft Large-Angle Attitude Maneuvering and Tracking.

This paper addresses the problem of large-angle attitude maneuvering and tracking control for rigid spacecraft, considering angular velocity and torque constraints, actuator faults, and external disturbances. First, a sliding-mode-like vector is constructed to guarantee the satisfaction of the angular velocity constraints. A modified preassigned finite-time function, which can adaptively adjust the boundaries, is then proposed to constrain the sliding-mode-like vector.

Uterine cystic adenomyosis: a case report.

Background: Uterine cystic adenomyosis (CA) is a unique form of adenomyosis with a single or fused lumen of the cystic space exceeding a diameter of 1 cm that typically results in progressively worsening dysmenorrhea. In most cases, the prognosis and pregnancy outcomes of CA remained unclear, and therefore further studies are warranted.

Case Description: A 19‑year‑old woman was admitted for irregular vaginal bleeding that lasted for more than one month.

An empirical study of LLaMA3 quantization: from LLMs to MLLMs.

The LLaMA family, a collection of foundation language models ranging from 7B to 65B parameters, has become one of the most powerful open-source large language models (LLMs) and the popular LLM backbone of multi-modal large language models (MLLMs), widely used in computer vision and natural language understanding tasks. In particular, LLaMA3 models have recently been released and have achieved impressive performance in various domains with super-large scale pre-training on over 15T tokens of data. Given the wide application of low-bit quantization for LLMs in resource-constrained scenarios, we explore LLaMA3's capabilities when quantized to low bit-width.

Epidemiological insights into severe hepatitis in pediatric inpatients.

There is limited statistical data on severe hepatitis among hospitalized children in China at a national level. This nationwide study analyzed data from 34,410 children hospitalized for severe hepatitis in mainland China from 2016 to 2022. The overall in-hospital mortality rate was 6.

A natural gelatin/casein hydrogel with on-demand adhesion via chitosan solution for wound healing.

Adhesive hydrogels have been widely studied as wound dressings due to their excellent biocompatibility and biological activity. However, most designed hydrogels still exist limitations including potentially toxic monomer, complex preparation process and non-degradable property. Here, a natural and degradable gelatin/casein hydrogel was prepared by enzymatic cross-linking.

Phylogenomics and adaptive evolution of hydrophytic umbellifers (tribe Oenantheae, Apioideae) revealed from chloroplast genomes.

Background: Tribe Oenantheae consists mainly of aquatic species within the Apioideae. The unique morphology and habitat distinguish this group from other Apioideae groups. However, the genomic information of these group species has not been widely developed, and the molecular mechanisms of adaptive evolution remain unclear.

Electromagnetic Navigation Improves Accuracy and Reduces Complications of Ventriculoperitoneal Shunts in Patients with Idiopathic Normal Pressure Hydrocephalus: A Single-Center Clinical Experience.

Background: Ventriculoperitoneal (VP) shunt surgery is the primary treatment for patients with idiopathic normal pressure hydrocephalus (iNPH). This study compared the outcomes of VP shunt placement using electromagnetic (EM) navigation versus standard methods in patients with iNPH, focusing on catheter accuracy and postoperative complication rates.

Methods: This retrospective study included 31 patients with iNPH who underwent standard shunt placement using anatomical landmarks and 50 patients who underwent EM-guided shunt placement.

Childhood-onset systemic lupus erythematosus in China, 2016-21: a nationwide study.

Background: Childhood-onset systemic lupus erythematosus (SLE) is a complex autoimmune disorder that can lead to serious organ damage. Despite the prevalence of SLE among children in Asian countries, treatment guidelines, prognosis, and clinical decision making for children with SLE are limited by gaps in region-specific epidemiological data. The aim of this study was to analyse epidemiological characteristics of childhood-onset SLE and associated organ involvement and in-hospital mortality in China.

Improved mapping of heavy metals in agricultural soils using machine learning augmented with spatial regionalization indices.

The accurate spatial mapping of heavy metal levels in agricultural soils is crucial for environmental management and food security. However, the inherent limitations of traditional interpolation methods and emerging machine-learning techniques restrict their spatial prediction accuracy. This study aimed to refine the spatial prediction of heavy metal distributions in Guangxi, China, by integrating machine learning models and spatial regionalization indices (SRIs).

Lipid metabolites abnormally expressed in pelvic fluid as potential biomarkers for ovarian cancer: A case-control study.

Background: Ovarian cancer is insidious and usually detected in advanced stages of the disease. As the ovaries are pelvic organs, changes in their pelvic fluid metabolites may be associated with ovarian cancer.

Methods: Metabolomic changes in the pelvic fluid were detected using liquid chromatography-tandem mass spectrometry (LC-MS/MS) in patients with ovarian cancer, ovarian cysts and uterine fibroids.

Electrohydrodynamic Direct-Writing Micro/Nanofibrous Architectures: Principle, Materials, and Biomedical Applications.

Electrohydrodynamic (EHD) direct-writing has recently gained attention as a highly promising additive manufacturing strategy for fabricating intricate micro/nanoscale architectures. This technique is particularly well-suited for mimicking the extracellular matrix (ECM) present in biological tissue, which serves a vital function in facilitating cell colonization, migration, and growth. The integration of EHD direct-writing with other techniques has been employed to enhance the biological performance of scaffolds, and significant advancements have been made in the development of tailored scaffold architectures and constituents to meet the specific requirements of various biomedical applications.

SOFA in sepsis: with or without GCS.

Purpose: Sepsis is a global public health burden. The sequential organ failure assessment (SOFA) is the most commonly used scoring system for diagnosing sepsis and assessing severity. Due to the widespread use of endotracheal intubation and sedative medications in sepsis, the accuracy of the Glasgow Coma Score (GCS) is the lowest in SOFA.

Development and status quo of digestive endoscopy in China: An analysis based on the national census in 2013 and 2020.

Background And Objectives: Technique and practice of digestive endoscopy are undergoing speedy development all over the world. This study aimed to evaluate its status quo and development in China.

Methods: All hospitals performing digestive endoscopy in mainland China participated in the national census in 2013 and 2020.

Comparative Analysis of Postoperative Sagittal Balance in Expansive Open-Door Laminoplasty versus Laminectomy with Fusion for Multilevel Ossification of Posterior Longitudinal Ligament: A Retrospective Study.

BACKGROUND This single-center study included 80 patients with multilevel cervical ossification of the posterior longitudinal ligament (OPLL) and aimed to compare postoperative sagittal balance following treatment with expansive open-door laminoplasty (LP) vs total laminectomy with fusion (LF). MATERIAL AND METHODS Data of 80 patients with multilevel OPLL treated with LP vs LF between January 2017 and January 2022 were retrospectively analyzed. The basic data, cervical sagittal parameters, and clinical outcomes of the patients were counted in the preoperative and postoperative periods, and complications were recorded.

Thermally-resilient, phase-invertible, ultra-stable all-aqueous compartments by pH-modulated protein colloidal particles.

The essence of compartmentalization in cells is the inspiration behind the engineering of synthetic counterparts, which has emerged as a significant engineering theme. Here, we report the formation of ultra-stable water-in-water (W/W) emulsion droplets. These W/W droplets demonstrate previously unattained stability across a broad pH spectrum and exhibit resilience at temperatures up to 80℃, overcoming the challenge of insufficient robustness in dispersed droplets of aqueous two-phase systems (ATPS).

Identification and validation of IRF6 related to ovarian cancer and biological function and prognostic value.

Background: Ovarian cancer (OC) is a severe gynecological malignancy with significant diagnostic and therapeutic challenges. The discovery of reliable cancer biomarkers can be used to adjust diagnosis and improve patient care. However, serous OC lacks effective biomarkers.

Association of medical care capacity and the patient mortality of septic shock: a cross-sectional study.

Background: Hospitals with higher septic shock case volume demonstrated lower hospital mortality. We conducted this study to investigate whether this phenomenon was only caused by the increase in the number of admissions or the need to improve the medical care capacity in septic shock at the same time.

Methods: Seven-hundred and eighty-seven hospitals from China collected in a survey from January 1, 2021 to December 31, 2021.

Multicompartmental coacervate-based protocell by spontaneous droplet evaporation.

Hierarchical compartmentalization, a hallmark of both primitive and modern cells, enables the concentration and isolation of biomolecules, and facilitates spatial organization of biochemical reactions. Coacervate-based compartments can sequester and recruit a large variety of molecules, making it an attractive protocell model. In this work, we report the spontaneous formation of core-shell cell-sized coacervate-based compartments driven by spontaneous evaporation of a sessile droplet on a thin-oil-coated substrate.

Health economic analysis and medical cost analysis of children with severe hepatitis B in China: A retrospective study from 2016 to 2022.

Background: Hepatitis B poses a heavy burden for children in China, however, the national studies on the distributional characteristics and health care costs of children with severe hepatitis B is still lacking. This study aimed to analyze the disease characteristics, health economic effects, and medical cost for children with severe hepatitis B in China.

Methods: Based on patient information in the Hospital Quality Monitoring System, cases with severe hepatitis B were divided into four groups according to age, and the etiology and symptoms of each group were quantified.

Quality indicators for epilepsy management in China: The development of a tool to assess care and first three-year report.

Objectives: Epilepsy care in China has expanded considerably in the last decade but still remains largely unknown; we developed an easy-to-use tool to assess its quality.

Methods: We adapted the Epilepsy Update Quality Measurement, produced by the American Academy of Neurology (AAN) for use in China: The Quality Indicator for Epilepsy Treatment-China National Action (QUIET-CHINA). This tool incorporates a standardized case report form initially for logging quality indicators for people with epilepsy during in-patient stays.