Publications by authors named "Xudong Cha"
Background: Parapharyngeal space tumor is a tumor that occurs in the parapharyngeal space. Parapharyngeal space tumors are uncommon, accounting for about 0.5% of head and neck tumors.
View Article and Find Full Text PDFA cross-sectional study on predictors of patients' tinnitus severity.
World J Otorhinolaryngol Head Neck Surg
September 2024
Article Synopsis
- The study aimed to identify factors influencing tinnitus severity using a multiple linear regression model based on data from 331 patients visiting a hospital between 2019 and 2021.
- Results showed significant positive correlations between tinnitus severity and factors like loudness, anxiety (measured by SAS scores), and sleep quality (measured by PSQI scores).
- The findings suggest that effectively managing tinnitus requires addressing these factors, as they play a crucial role in predicting the severity of the condition.
Taste perception is one of the important senses in mammals. Taste dysfunction causes significant inconvenience in daily life, leading to subhealth and even life-threatening condition. Aging is a major cause to taste dysfunction, while the underlying feature related to gustatory aging is still not known.
View Article and Find Full Text PDFArticle Synopsis
- This study aimed to create a radiomics nomogram that uses MRI features and clinical data to differentiate between pleomorphic adenoma (PA) and warthin tumor (WT).
- It involved analyzing data from 294 patients, extracting MRI radiomics features, and establishing a combined model that includes both clinical factors and radiomics scores.
- The combined model showed superior accuracy in distinguishing PA from WT compared to standalone clinical and radiomics models, demonstrating excellent performance in training and testing phases.
SIRT5 exacerbates eosinophilic chronic rhinosinusitis by promoting polarization of M2 macrophage.
J Allergy Clin Immunol
September 2024
Background: Previous studies implied that local M2 polarization of macrophage promoted mucosal edema and exacerbated T2 type inflammation in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the specific pathogenic role of M2 macrophages and the intrinsic regulators in the development of CRS remains elusive.
Objective: We sought to investigate the regulatory role of SIRT5 in the polarization of M2 macrophages and its potential contribution to the development of CRSwNP.
Objective: Differentiating 2 types of chronic rhinosinusitis with nasal polyps (CRSwNP) is important for the treatment. The current diagnostic methods using single indicators, including peripheral blood eosinophils and traditional sinus computed tomography (CT) scores, are not accurate. In this study, we aimed to investigate the diagnostic value of combining peripheral blood eosinophils and improved sinus CT scores for eosinophic chronic rhinosinusitis (ECRS).
View Article and Find Full Text PDFGustation is important to several biological functions in mammals. However, chemotherapy drugs often harm taste perception in cancer patients, while the underlying mechanism is still unclear for most drugs and there is no effective way to restore taste function. This study investigated the effects of cisplatin on the taste cell homeostasis and gustatory function.
View Article and Find Full Text PDFObjective: We aimed to evaluate the effectiveness of topical tranexamic acid (TXA) versus topical vasoconstrictors in the management of epistaxis via a systematic review and meta-analysis.
Methods: The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) standards were followed for the meta-analysis. We systematically searched Embase, Web of Science, Cochrane Library, CNKI, and PubMed for randomized controlled trials (from inception to August 2022; no language restrictions), comparing the effect of topical TXA and topical vasoconstrictors on the treatment of epistaxis.
Objective: To investigate the characteristics of sleep disorders and anxiety in patients with tinnitus, their influencing factors, and the role of sleep disorders as mediators.
Methods: The general conditions and disease characteristics of 393 patients with tinnitus presented to the Changzheng Hospital of the Naval Medical University from 2018 to 2021 were collected. All patients accepted questionnaires such as Tinnitus Handicap Inventory (THI), Pittsburgh Sleep Quality Index (PSQI) and Self-rating Anxiety Scale (SAS), and then the characteristics and the influencing factors of sleep disorders and anxiety were analyzed.
The prevention and control of human immunodeficiency virus (HIV) infection is important for public health. Sexual contact transmission has replaced blood transmission as a major route of HIV transmission in China. The incidence of HIV infection increased significantly among young men who have sex with men (MSM).
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