Publications by authors named "Xuchun Liu"

Article Synopsis
  • A four-year-old boy experienced recurrent fever and severe pneumonia due to a reassortant avian influenza A-H3N8 virus, identified through high-throughput sequencing.
  • The virus displayed avian gene characteristics and internal genes from H9N2 strains, suggesting increased virulence and ability to infect mammals, with the child suffering from multiple organ dysfunction and requiring intensive medical support.
  • Although H3N8 RNA was found in pets and the environment around the boy, there were no signs of illness in family members, indicating that person-to-person transmission is unlikely, highlighting the need for ongoing monitoring of avian influenza threats.
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FATP1 plays an important role in the regulation of fatty acid metabolism and lipid accumulation. In this study, we investigated the patterns of expression in various tissues obtained from calf and adult Qinchuan cattle, and in differentiating adipocytes. Next, we investigated the effect of expression on preadipocyte differentiation in Qinchuan cattle using overexpression and interference assays.

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Article Synopsis
  • Carbapenem-resistant Enterobacteriaceae (CRE) are a significant public health threat, and this study analyzed 12 strains producing the IMP-4 metallo-β-lactamase from a hospital in Zhengzhou between 2013 and 2015.
  • All isolates were found to be multidrug-resistant but susceptible to colistin, revealing that most belonged to the ST167 sequence type, with varied plasmid types predominantly consisting of N types.
  • The study highlighted the stability and transferability of N-type plasmids, identifying a near-identical plasmid to one linked with an epidemic strain, and noted a conserved transposon-like structure among the plasmids involved in resistance.
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Case Presentation: We report the first confirmed case of the novel coronavirus disease (COVID-19) in a lactating patient in Chizhou, Anhui Province, China. The lactating patient presented with intermittent fever for 16 days and cough for 10 days. Given her travel history to the epidemic area and the chest CT scan results, the patient was immediately admitted to the isolation ward of the Infectious Disease Department and breastfeeding was discontinued.

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Although numerous studies investigated the effect of UASMS2 polymorphism in leptin gene on cattle production, a consensus has not yet been reached. Therefore, we reviewed and meta-analyzed the effects of UASMS2 on cattle. We searched potentially relevant studies from seven databases (to December 25, 2019).

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Myogenic factor 5 plays actively roles in the regulation of myogenesis. The aims of this study are to identify the evolution information of MYF5 protein among 10 domestic and mammalian animals, to uncover the expression patterns of MYF5 gene in calves and adults of Qinchuan cattle, and to expose the genetic variants of the MYF5 gene and explore its effect on cattle growth traits and beef quality traits in Qinchuan cattle. The bioinformatics results showed that the MYF5 proteins highly conserved in different mammalian or domestic animals apart from chicken.

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Rationale: The clinical manifestations in patients with bronchial tuberculosis (BTB) are nonspecific and may pose a great diagnostic challenge.

Patient Concerns: Here we describe the case of a 57-year-old man presented with right chest pain, chest tightness, and discomfort for 2 days.

Diagnosis: Bronchoscopic biopsy was performed which revealed subepithelial and epithelioid cell granuloma of Langerhans cell structure.

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Shikonin (SHK) is a natural naphthoquinone pigment isolated from , that has been reported to suppress the growth of a number of cancer cell types. Adriamycin (AD) is typically used as an effective anticancer agent; however, it has the propensity to induce drug resistance. The aim of the present study was to investigate the effects of SHK alone and in combination with AD on lung adenocarcinoma cells and the underlying molecular mechanisms of their effects.

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Context: Histiocytic necrotizing lymphadenitis (HNL) is a rare disorder that is often benign and self-limiting. There have been reports of co-occurrence of HNL with other diseases, including systemic lupus erythematosus, hemophagocytic syndrome and antiphospholipid syndrome.

Case Report: Here, we report a case in which a patient experienced unexplained fever, swelling of the cervical lymph node and bilateral pleural effusion and was ultimately diagnosed with HNL based on results from a lymph node biopsy.

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Pulmonary cryptococcosis (PC) is a relatively rare infectious disease. It mainly involves the lungs; however, in some patients, the infection could spread to other parts of the body. PC mostly occurs in patients with immune deficiencies.

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The emergence of New Delhi metallo-β-lactamase 1 (NDM-1) has become established as a major public health threat and represents a new challenge in the treatment of infectious diseases. In this study, we report a high incidence and endemic spread of NDM-1-producing carbapenem-resistant Enterobacter cloacae isolates in Henan province, China. Eight (72.

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Bioassay-guided fractionation against alpha-glucosidase resulted in isolation and identification of six phenolic compounds (1-6) from the 70% EtOH extract of the roots of Solanum melongena L. (Solanaceae). Of these, three phenylethyl cinnamides, N-trans-feruloyl tyramine (1), N-trans-p-coumaroyl tyramine (2) and N-cis-p-coumaroyl tyramine (3) possessed inhibitory activity against alpha-glucosidase with IC50 values of 500.

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