Publications by authors named "Xuanzhu Chen"

Primary angle closure disease (PACD) is a major cause of blindness worldwide. It has a high prevalence in East Asia, especially in China, which leads to a higher incidence of blindness than open-angle glaucoma. The aim of this study was to directly observe the circumlental space (CLS) in laser peripheral iridotomized eyes with PACD and to determine whether this structure plays a role in the pathogenesis of PACD.

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Introduction: Astigmatism reduces the postoperative visual performance after non-toric intraocular lenses (IOLs) implantation, and limits the use of refractive IOLs in cataract surgery. The purpose of this study was to compare the efficacy in astigmatism correction and the postoperative visual outcomes between the implantation of a trifocal IOL with femtosecond laser-assisted arcuate keratotomy (FSAK) in one eye and a bifocal toric IOL (TIOL) in the other, in patients with cataract and moderate astigmatism.

Methods: This prospective observational paired-eye study enrolled patients with cataract and corneal astigmatism (CA) between 0.

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Background: Pigmented paravenous retinochoroidal atrophy (PPRCA) is an uncommon fundus disease characterized by perivenous aggregations of pigment clumps and retinochoroidal atrophy distributed along the retinal veins. We report a Chinese female case of unilateral PPRCA with acute angle-closure glaucoma (AACG).

Case Presentation: A 50-year-old Chinese female presented with vision loss and elevated intraocular pressure (IOP) in the right eye and then underwent trabeculectomy.

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Purpose: To investigate the presence of the vitreous zonule (VZ) in different subtypes of primary angle-closure disease (PACD) and to explore the relationship between VZ and anterior chamber angle characteristics.

Methods: Patients with clinical diagnoses of acute primary angle-closure (PAC)/PAC glaucoma (APAC[G]) or chronic PAC/PAC glaucoma (CPAC[G]) and healthy subjects were enrolled. A total of 300 eyes of 180 subjects were included.

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Article Synopsis
  • XEN gel stents are designed for treating open-angle glaucoma (OAG) when other treatments have failed, with a focus on evaluating their impact on intraocular pressure (IOP), medication needs, and safety.
  • A systematic review of 56 relevant studies involving 4,410 eyes showed that the stents significantly reduced IOP by about 35% and decreased the need for antiglaucoma medications.
  • The treatment demonstrated a good safety profile, with less than 1% incidence of serious complications, while achieving a complete success rate of 21.0-70.8% over two years.
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