Publications by authors named "Xuanqi Zhu"
Exogenous iron delivery using iron-containing nanomaterials is an alternative strategy for enhancing the efficacy in ferroptosis tumor therapy but limited by the problems of low iron content, low tumor enrichment, low cellular uptake, and uncontrolled release of iron ions. To solve the problems, an FeOOH-assisted approach is demonstrated to produce iron hybrid polymer nanospindles (IHPNSs) for efficient iron delivery and ferroptosis tumor therapy. The IHPNSs are prepared through the cohydrolysis of FeCl·6HO with aniline, pyrrole, or amino-pyrrole.
View Article and Find Full Text PDFType-I Collagen Polypeptide-Based Composite Nanofiber Membranes for Fast and Efficient Bone Regeneration.
ACS Biomater Sci Eng
September 2024
Article Synopsis
- The treatment of bone defects has traditionally relied on allogeneic and autologous bone transplants, which both have limitations, prompting the exploration of bone tissue engineering using various scaffold materials.
- Recent advancements in scaffolds have faced challenges like biotoxicity and inflammation that impair their effectiveness in promoting bone regeneration.
- This study developed a new type of collagen-based nanofiber membrane that, in experiments, showed low toxicity and significantly enhanced bone cell differentiation and regeneration, leading to complete healing of bone defects in about two months.