Preserving functional lung using perfusion imaging and intensity-modulated radiation therapy for advanced-stage non-small cell lung cancer.

Purpose: To assess quantitatively the impact of incorporating functional lung imaging into intensity-modulated radiation therapy planning for locally advanced non-small cell lung cancer (NSCLC).

Methods And Materials: Sixteen patients with advanced-stage NSCLC who underwent radiotherapy were included in this study. Before radiotherapy, each patient underwent lung perfusion imaging with single-photon-emission computed tomography and X-ray computed tomography (SPECT-CT).

The prevalence of myocardial ischemia after concurrent chemoradiation therapy as detected by gated myocardial perfusion imaging in patients with esophageal cancer.

Unlabelled: The detection of myocardial perfusion abnormalities after radiation therapy (RT) has been investigated previously in patients with lymphoma and breast cancer. However, the prevalence and association of such abnormalities with RT in esophageal cancer patients have not been investigated previously.

Methods: The prevalence of myocardial perfusion abnormalities detected using gated myocardial perfusion imaging (GMPI) in patients with esophageal cancer after RT (RT group) was compared with that in patients with esophageal cancer who did not undergo RT (NRT group).