Publications by authors named "Xuangu Liu"
J Infect Dis
December 2024
Article Synopsis
- The study examined drug resistance in HIV among newly diagnosed individuals in China from 2018 to 2023 to adapt treatment guidelines.
- Out of over 22,000 individuals, 4.36% had at least one transmitted drug resistance (TDR) mutation, with the most common being linked to nonnucleoside reverse transcriptase inhibitors.
- The prevalence of TDR mutations notably increased from 4.05% to 5.39% over the study years, supporting the ongoing use of NNRTI-based treatment regimens for HIV.
J Infect Dis
November 2024
Article Synopsis
- China adopted the WHO's "treat all" policy in 2016, aiming to improve HIV care through the 95-95-95 targets, which include diagnosing 95% of HIV positive individuals, getting 95% of those diagnosed on treatment, and achieving viral suppression in 95% of treated individuals.
- Data from 2004 to 2023 showed significant advancements in these targets, correlating with a drop in new HIV infections, as evidenced by a dip in clustering frequency and a peak in cases documented in 2014.
- The study concludes that while progress has been made, China needs to focus on increasing efforts in the first "95" target to further reduce HIV transmission rates and improve overall outcomes.
